Ranked #1
33. Green Chemistry. Acids and Acid Derivatives
33. Green Chemistry. Acids and Acid Derivatives
Green chemistry needs new asymmetric reactions and safer, more environmental Mitsunobu reactions. The Mitsunobu mechanis... Read more
2 Apr 2012
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49mins
Ranked #2
35. Acyl Insertions and [gr]α-Reactivity
35. Acyl Insertions and [gr]α-Reactivity
When a nucleophilic atom bearing a good leaving group attacks a carbonyl group, an adjacent R group can migrate to the n... Read more
2 Apr 2012
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48mins
Ranked #3
36. [gr]α-Reactivity and Condensation Reactions
36. [gr]α-Reactivity and Condensation Reactions
As in many synthetic procedures, an important challenge in ketone alkylation is choosing reagents and conditions that al... Read more
2 Apr 2012
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53mins
Ranked #4
32. Measuring Bond Energies: Guest Lecture by Prof. G. Barney Ellison
32. Measuring Bond Energies: Guest Lecture by Prof. G. Barney Ellison
Spectroscopic determination of bond dissociation energies is relatively straightforward for many diatomic molecules, but... Read more
2 Apr 2012
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47mins
Ranked #5
30. Oxidation States and Mechanisms
30. Oxidation States and Mechanisms
A difficult exam question shows how visible and NMR spectroscopy related to long-term misassignment of the structure for... Read more
2 Apr 2012
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46mins
Ranked #6
29. Imines and Enamines. Oxidation and Reduction
29. Imines and Enamines. Oxidation and Reduction
Imines are pervasive in chemistry and biology, playing key roles both the in artificial Strecker synthesis of amino acid... Read more
2 Apr 2012
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50mins
Ranked #7
28. Mechanism and Equilibrium of Carbonyl Reactions
28. Mechanism and Equilibrium of Carbonyl Reactions
This lecture aims at developing facility with devising plausible mechanisms for acid- and base-catalyzed reactions of ca... Read more
2 Apr 2012
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49mins
Ranked #8
26. Aromatic Substitution in Synthesis: Friedel-Crafts and Moses Gomberg
26. Aromatic Substitution in Synthesis: Friedel-Crafts and Moses Gomberg
The Friedel-Crafts reaction creates new alkyl- or acyl-aromatic bonds, with or without cation rearrangement. Designing r... Read more
2 Apr 2012
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50mins
Ranked #9
25. C-13 and 2D NMR. Electrophilic Aromatic Substitution
25. C-13 and 2D NMR. Electrophilic Aromatic Substitution
Proton decoupling simplifies C-13 NMR spectra. Dilute double labeling with C-13 confirmed the complex rearrangement sche... Read more
2 Apr 2012
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50mins
Ranked #10
24. Higher-Order Effects, Dynamics, and the NMR Time Scale
24. Higher-Order Effects, Dynamics, and the NMR Time Scale
Because spin-spin splitting depends on electron spin precisely at a nucleus, splitting by a C-13 depends on its orbital’... Read more
2 Apr 2012
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51mins
Ranked #11
23. Diamagnetic Anisotropy and Spin-Spin Splitting
23. Diamagnetic Anisotropy and Spin-Spin Splitting
Through-space interaction between magnets of fixed strength and orientation averages to zero during random molecular tum... Read more
2 Apr 2012
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48mins
Ranked #12
22. Medical MRI and Chemical NMR
22. Medical MRI and Chemical NMR
Magnetic resonance imaging (MRI) requires gradients in the applied magnetic field, while chemical nuclear magnetic reson... Read more
2 Apr 2012
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49mins
Ranked #13
21. Functional Groups and Fingerprints in IR Spectroscopy. Precession of Magnetic Nuclei
21. Functional Groups and Fingerprints in IR Spectroscopy. Precession of Magnetic Nuclei
Infrared spectroscopy provides information for analyzing molecular structure and for understanding bonding and dynamics.... Read more
2 Apr 2012
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53mins
Ranked #14
20. Electronic and Vibrational Spectroscopy
20. Electronic and Vibrational Spectroscopy
Time-dependent quantum mechanics shows how mixing orbitals of different energy causes electrons to vibrate. Mixing 1s w... Read more
2 Apr 2012
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49mins
Ranked #15
19. Aromatic Transition States: Cycloaddition and Electrocyclic Reactions
19. Aromatic Transition States: Cycloaddition and Electrocyclic Reactions
Cyclic conjugation that arises when p-orbitals touch one another can be as important for transition states as aromaticit... Read more
2 Apr 2012
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49mins