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Freshman Organic Chemistry 2

Freshman Organic Chemistry 2

Ranked #1

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33. Green Chemistry. Acids and Acid Derivatives

33. Green Chemistry. Acids and Acid Derivatives

Green chemistry needs new asymmetric reactions and safer, more environmental Mitsunobu reactions. The Mitsunobu mechanis... Read more

2 Apr 2012

49mins

Ranked #2

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35. Acyl Insertions and [gr]α-Reactivity

35. Acyl Insertions and [gr]α-Reactivity

When a nucleophilic atom bearing a good leaving group attacks a carbonyl group, an adjacent R group can migrate to the n... Read more

2 Apr 2012

48mins

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Ranked #3

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36. [gr]α-Reactivity and Condensation Reactions

36. [gr]α-Reactivity and Condensation Reactions

As in many synthetic procedures, an important challenge in ketone alkylation is choosing reagents and conditions that al... Read more

2 Apr 2012

53mins

Ranked #4

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32. Measuring Bond Energies: Guest Lecture by Prof. G. Barney Ellison

32. Measuring Bond Energies: Guest Lecture by Prof. G. Barney Ellison

Spectroscopic determination of bond dissociation energies is relatively straightforward for many diatomic molecules, but... Read more

2 Apr 2012

47mins

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Ranked #5

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30. Oxidation States and Mechanisms

30. Oxidation States and Mechanisms

A difficult exam question shows how visible and NMR spectroscopy related to long-term misassignment of the structure for... Read more

2 Apr 2012

46mins

Ranked #6

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29. Imines and Enamines. Oxidation and Reduction

29. Imines and Enamines. Oxidation and Reduction

Imines are pervasive in chemistry and biology, playing key roles both the in artificial Strecker synthesis of amino acid... Read more

2 Apr 2012

50mins

Ranked #7

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28. Mechanism and Equilibrium of Carbonyl Reactions

28. Mechanism and Equilibrium of Carbonyl Reactions

This lecture aims at developing facility with devising plausible mechanisms for acid- and base-catalyzed reactions of ca... Read more

2 Apr 2012

49mins

Ranked #8

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26. Aromatic Substitution in Synthesis: Friedel-Crafts and Moses Gomberg

26. Aromatic Substitution in Synthesis: Friedel-Crafts and Moses Gomberg

The Friedel-Crafts reaction creates new alkyl- or acyl-aromatic bonds, with or without cation rearrangement. Designing r... Read more

2 Apr 2012

50mins

Ranked #9

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25. C-13 and 2D NMR. Electrophilic Aromatic Substitution

25. C-13 and 2D NMR. Electrophilic Aromatic Substitution

Proton decoupling simplifies C-13 NMR spectra. Dilute double labeling with C-13 confirmed the complex rearrangement sche... Read more

2 Apr 2012

50mins

Ranked #10

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24. Higher-Order Effects, Dynamics, and the NMR Time Scale

24. Higher-Order Effects, Dynamics, and the NMR Time Scale

Because spin-spin splitting depends on electron spin precisely at a nucleus, splitting by a C-13 depends on its orbital’... Read more

2 Apr 2012

51mins

Ranked #11

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23. Diamagnetic Anisotropy and Spin-Spin Splitting

23. Diamagnetic Anisotropy and Spin-Spin Splitting

Through-space interaction between magnets of fixed strength and orientation averages to zero during random molecular tum... Read more

2 Apr 2012

48mins

Ranked #12

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22. Medical MRI and Chemical NMR

22. Medical MRI and Chemical NMR

Magnetic resonance imaging (MRI) requires gradients in the applied magnetic field, while chemical nuclear magnetic reson... Read more

2 Apr 2012

49mins

Ranked #13

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21. Functional Groups and Fingerprints in IR Spectroscopy. Precession of Magnetic Nuclei

21. Functional Groups and Fingerprints in IR Spectroscopy. Precession of Magnetic Nuclei

Infrared spectroscopy provides information for analyzing molecular structure and for understanding bonding and dynamics.... Read more

2 Apr 2012

53mins

Ranked #14

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20. Electronic and Vibrational Spectroscopy

20. Electronic and Vibrational Spectroscopy

Time-dependent quantum mechanics shows how mixing orbitals of different energy causes electrons to vibrate. Mixing 1s w... Read more

2 Apr 2012

49mins

Ranked #15

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19. Aromatic Transition States: Cycloaddition and Electrocyclic Reactions

19. Aromatic Transition States: Cycloaddition and Electrocyclic Reactions

Cyclic conjugation that arises when p-orbitals touch one another can be as important for transition states as aromaticit... Read more

2 Apr 2012

49mins

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