Nels and Vincent explain a study of how interspecies competition between two algae influences evolution of metabolism and size. Hosts: Nels Elde and Vincent Racaniello Subscribe (free):  Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode •Join the MicrobeTV Discord server • Metabolic evolution during competition (Curr Biol) Science Picks Nels – How amino acids got their names (Source) Vincent – EVs Fix One Pollution Problem—And Worsen Another Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent explain a study of how interspecies competition between two algae influences evolution of metabolism and size. Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://podcasts.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank"> Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode •Join the <a href="https://discord.gg/vmnCyBPQds" rel="nofollow" target="_blank">MicrobeTV Discord server</a> • <a href="https://www.cell.com/current-biology/fulltext/S0960-9822(23)00777-7?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982223007777%3Fshowall%3Dtrue" rel="nofollow" target="_blank">Metabolic evolution</a> during competition (Curr Biol) Science Picks Nels – <a href="https://twitter.com/chupvl/status/1310628876691927040" rel="nofollow" target="_blank">How amino acids got their names</a> (<a href="https://www.etymologynerd.com/" rel="nofollow" target="_blank">Source</a>) Vincent – <a href="https://www.theatlantic.com/technology/archive/2023/07/electric-vehicles-tires-wearing-out-particulates/674750/" rel="nofollow" target="_blank">EVs Fix One Pollution Problem—And Worsen Another</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 92: There's algae in the jar

Nels and Vincent discuss new findings using phylogenetic approaches about how complex eukaryotic cells emerged from prokaryotic ancestors, which firmly place eukaryotes as a clade nested within the Asgard archaea. Hosts: Nels Elde and Vincent RacanielloS Subscribe (free):  Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode •Join the MicrobeTV Discord server •Heimdallarchaeial ancestry of eukaryotes (Nature) Science Picks Nels – Juneteenth issue of Cell – collection of essays from black and brown scientists Vincent – Tara Oceans Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent discuss new findings using phylogenetic approaches about how complex eukaryotic cells emerged from prokaryotic ancestors, which firmly place eukaryotes as a clade nested within the Asgard archaea. Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a>S Subscribe (free): <a href="https://podcasts.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank"> Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode •Join the <a href="https://discord.gg/vmnCyBPQds" rel="nofollow" target="_blank">MicrobeTV Discord server</a> •Heimdallarchaeial <a href="https://www.nature.com/articles/s41586-023-06186-2" rel="nofollow" target="_blank">ancestry of eukaryotes</a> (Nature) Science Picks Nels – <a href="https://www.cell.com/cell/fulltext/S0092-8674(23)00536-6" rel="nofollow" target="_blank">Juneteenth issue of Cell – collection of essays from black and brown scientists</a> Vincent – <a href="https://fondationtaraocean.org/en/expedition/tara-oceans/" rel="nofollow" target="_blank">Tara Oceans</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 91: Meet your very distant cousins

Nels and Vincent provide insights into the mystery of mouse mummies on the summits of &gt;6000 m Andean volcanoes, including whether they were living there and if so why? Hosts: Nels Elde and Vincent Racaniello Subscribe (free):  Apple Podcasts,  Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode •Join the MicrobeTV Discord server •Mystery of mouse mummies (bioRxiv) Science Picks Nels – Zoonomia Vincent – SeaPhages Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent provide insights into the mystery of mouse mummies on the summits of &gt;6000 m Andean volcanoes, including whether they were living there and if so why? Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://podcasts.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank"> Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank"> Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode •Join the <a href="https://discord.gg/vmnCyBPQds" rel="nofollow" target="_blank">MicrobeTV Discord server</a> •Mystery of <a href="https://www.biorxiv.org/content/10.1101/2023.04.22.537927v1" rel="nofollow" target="_blank">mouse mummies</a> (bioRxiv) Science Picks Nels – <a href="https://zoonomiaproject.org/" rel="nofollow" target="_blank">Zoonomia</a> Vincent – <a href="https://seaphages.org/" rel="nofollow" target="_blank">SeaPhages</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 90: The mystery of the mouse mummies

Nels and Vincent discuss the observation that cells on a boundary of a solid tumor have higher growth rates compared to those in the center and how to model this difference using genome sequencing data. Hosts: Nels Elde and Vincent Racaniello Subscribe (free):  Apple Podcasts,  Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode •Join the MicrobeTV Discord server •Evolutionary models of solid tumor growth (Nat Ecol Evol) Science Picks Nels – TWiV 1000 Vincent –  The dream of wiping out polio might need a rethink Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent discuss the observation that cells on a boundary of a solid tumor have higher growth rates compared to those in the center and how to model this difference using genome sequencing data. Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://podcasts.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank"> Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank"> Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode •Join the <a href="https://discord.gg/vmnCyBPQds" rel="nofollow" target="_blank">MicrobeTV Discord server</a> •Evolutionary models of <a href="https://www.nature.com/articles/s41559-023-02000-4" rel="nofollow" target="_blank">solid tumor growth</a> (Nat Ecol Evol) Science Picks Nels – <a href="https://www.microbe.tv/twiv/twiv-1000/" rel="nofollow" target="_blank">TWiV 1000</a> Vincent – <a href="https://www.npr.org/sections/goatsandsoda/2023/04/10/1168141163/the-dream-of-wiping-out-polio-might-need-a-rethink" rel="nofollow" target="_blank"> The dream of wiping out polio might need a rethink</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 89: On the outer rim of tumor evolution

Nels and Vincent review a study of the dogs of Chernobyl which reveals that genetically distinct populations with different amounts of western breed contributions to their genomes, the first step in assessing the effects of exposure to long-term ionizing radiation. Hosts: Nels Elde and Vincent Racaniello Subscribe (free):  Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode •Join the MicrobeTV Discord server •The dogs of Chernobyl (Science Adv) •What the dogs of Chernobyl can teach us (Stat) •Letters read on TWiEVO 88 Science Picks Nels – Hellbent documentary and Insufficient evidence for natural selection associated with the Black Death Vincent – BioRender Listener Pick Walter – Oded Rechavi and interview Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent review a study of the dogs of Chernobyl which reveals that genetically distinct populations with different amounts of western breed contributions to their genomes, the first step in assessing the effects of exposure to long-term ionizing radiation. Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://podcasts.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank"> Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode •Join the <a href="https://discord.gg/vmnCyBPQds" rel="nofollow" target="_blank">MicrobeTV Discord server</a> •<a href="https://www.science.org/doi/full/10.1126/sciadv.ade2537" rel="nofollow" target="_blank">The dogs</a> of Chernobyl (Science Adv) •What the dogs of Chernobyl <a href="https://www.statnews.com/2023/03/03/what-the-dogs-of-chernobyl-can-teach-us-about-life-at-the-edge/?utm_source=pocket-newtab-global-en-GB" rel="nofollow" target="_blank">can teach us</a> (Stat) •<a href="https://www.microbe.tv/twievo/twievo-88-letters" rel="nofollow" target="_blank">Letters read</a> on TWiEVO 88 Science Picks Nels – <a href="https://www.hellbentfilm.com/" rel="nofollow" target="_blank">Hellbent documentary</a> and <a href="https://www.biorxiv.org/content/10.1101/2023.03.14.532615v1" rel="nofollow" target="_blank">Insufficient evidence for natural selection associated with the Black Death</a> Vincent – <a href="https://www.biorender.com/" rel="nofollow" target="_blank">BioRender</a> Listener Pick Walter – <a href="https://en-lifesci.tau.ac.il/profile/odedrech_66" rel="nofollow" target="_blank">Oded Rechavi</a> and <a href="https://hubermanlab.com/dr-oded-rechavi-genes-and-the-inheritance-of-memories-across-generations/" rel="nofollow" target="_blank">interview</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 88: Dog days of evolution in the shadows of Chernobyl

Nathan Clark

Nathan joins Nels and Vincent to discuss his approach to understanding how species adopt novel traits to overcome challenges, and its application to identifying coding and noncoding sequence changes that underlie mammalian hairlessness. Hosts: Nels Elde and Vincent Racaniello Guest: Nathan Clark Subscribe (free):  Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode •Join the MicrobeTV Discord server •Gene loss in marine mammals (TWiEVO 34) •Gene change underlying mammalian hair loss (eLife) •Letters read on TWiEVO 87 Science Picks Nels – Local news coverage of Amanda, Maria, and Nathan’s paper Vincent – Discovering Retroviruses by Anna Marie Skalka Nathan – Genomics of Secondarily Temperate Adaptation in the Only Non-Antarctic Icefish Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Nathan joins Nels and Vincent to discuss his approach to understanding how species adopt novel traits to overcome challenges, and its application to identifying coding and noncoding sequence changes that underlie mammalian hairlessness. Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Guest: <a href="https://bioscience.utah.edu/faculty/clark-nathan/index.php" rel="nofollow" target="_blank">Nathan Clark</a> Subscribe (free): <a href="https://podcasts.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank"> Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode •Join the <a href="https://discord.gg/vmnCyBPQds" rel="nofollow" target="_blank">MicrobeTV Discord server</a> •Gene loss in marine mammals (<a href="https://www.microbe.tv/twievo/twievo-34/" rel="nofollow" target="_blank">TWiEVO 34</a>) •Gene change underlying <a href="https://elifesciences.org/articles/76911" rel="nofollow" target="_blank">mammalian hair loss</a> (eLife) •<a href="https://www.microbe.tv/twievo/twievo-87-letters" rel="nofollow" target="_blank">Letters read</a> on TWiEVO 87 Science Picks Nels – <a href="https://www.ksl.com/article/50565499/utah-professors-team-may-have-figured-out-why-we-lost-our-fur-coats" rel="nofollow" target="_blank">Local news coverage of Amanda, Maria, and Nathan’s paper</a> Vincent – <a href="https://www.amazon.com/Discovering-Retroviruses-Anna-Marie-Skalka/dp/0674971701/ref=sr_1_1?crid=10JP98LUKFATA&amp;keywords=discovering+retroviruses&amp;qid=1676992327&amp;sprefix=discovering+retroviruses%2Caps%2C64&amp;sr=8-1" rel="nofollow" target="_blank">Discovering Retroviruses</a> by Anna Marie Skalka Nathan – G<a href="https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msad029/7035026" rel="nofollow" target="_blank">enomics of Secondarily Temperate Adaptation in the Only Non-Antarctic Icefish</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 87: Nathan Clark's revolutionary hair care advice

Nels and Vincent discuss how evolution of changes in stop codon assignment might occur, and a novel mechanism for altering the meaning of translation stop codons discovered in a trypanosomatid with the apropos name, Blastocrithidia nonstop. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts,  Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode •Join the MicrobeTV Discord server •Novel stop codon reassignment mechanisms (Nature) Science Picks Nels – Protein Synthesis: An epic on the cellular level  Vincent – Widespread stop-codon recoding in bacteriophages may regulate translation of lytic genes discussed on TWiM 277 Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent discuss how evolution of changes in stop codon assignment might occur, and a novel mechanism for altering the meaning of translation stop codons discovered in a trypanosomatid with the apropos name, Blastocrithidia nonstop. Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://podcasts.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank">Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank"> Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode •Join the <a href="https://discord.gg/vmnCyBPQds" rel="nofollow" target="_blank">MicrobeTV Discord server</a> •Novel <a href="https://www.nature.com/articles/s41586-022-05584-2" rel="nofollow" target="_blank">stop codon reassignment</a> mechanisms (Nature) Science Picks Nels – <a href="https://www.youtube.com/watch?v=WTRmvnlNVw4" rel="nofollow" target="_blank">Protein Synthesis: An epic on the cellular level </a> Vincent – <a href="https://www.nature.com/articles/s41564-022-01128-6" rel="nofollow" target="_blank">Widespread stop-codon recoding in bacteriophages may regulate translation of lytic genes</a> discussed on <a href="https://www.microbe.tv/twim/twim-277/" rel="nofollow" target="_blank">TWiM 277</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 86: Pulling out the stops in genetic code evolution

Nels and Vincent discuss the use of genome sequence data for over 4,000 domestic, semi-feral, and wild canids to understand the genetic drivers of canine behavior. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode  Genetic drivers of canine diversification (Cell) Time stamps by Jolene. Thanks!  Science Picks Nels – Ghosts of Science Past Still Haunt Us by C. Brandon Ogbunu Vincent – The Biggest Ideas in the Universe by Sean Carroll Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent discuss the use of genome sequence data for over 4,000 domestic, semi-feral, and wild canids to understand the genetic drivers of canine behavior. Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://podcasts.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank">Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode <ul> <li>Genetic drivers of <a href="https://pubmed.ncbi.nlm.nih.gov/36493753/" rel="nofollow" target="_blank">canine diversification</a> (Cell)</li> <li>Time stamps by <a href="https://twitter.com/jrrmicro" rel="nofollow" target="_blank">Jolene</a>. Thanks!</li> </ul> Science Picks Nels – <a href="https://race.undark.org/articles/ghosts-of-science-past-still-haunt-us-we-can-put-them-to-rest" rel="nofollow" target="_blank">Ghosts of Science Past Still Haunt Us</a> by C. Brandon Ogbunu Vincent – <a href="https://amzn.to/3FfQUZH" rel="nofollow" target="_blank">The Biggest Ideas in the Universe</a> by Sean Carroll Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 85: Teaching old dogs new genetic tricks

Nels and Vincent review the use of ancient DNA to identify loci that may have been under selection during the Black Death by studying populations before, during, and after the pandemic. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts,  Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode  Evolution of immune genes associated with Black Death (Nature) ERAP2 and respiratory disease (medRxiv) Time stamps by Jolene. Thanks!  Science Picks Nels –  Interview with Paul Turner in Current Biology and  Map of the World if you are a fish Vincent – Smallpox and its eradication Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent review the use of ancient DNA to identify loci that may have been under selection during the Black Death by studying populations before, during, and after the pandemic. Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://podcasts.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank">Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank"> Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode <ul> <li>Evolution of immune genes associated with <a href="https://www.nature.com/articles/s41586-022-05349-x" rel="nofollow" target="_blank">Black Death</a> (Nature)</li> <li>ERAP2 and <a href="https://www.medrxiv.org/content/10.1101/2022.11.04.22281942v1" rel="nofollow" target="_blank">respiratory disease</a> (medRxiv)</li> <li>Time stamps by <a href="https://twitter.com/jrrmicro" rel="nofollow" target="_blank">Jolene</a>. Thanks!</li> </ul> Science Picks Nels – <a href="https://www.cell.com/current-biology/fulltext/S0960-9822(22)01613-X#relatedArticles" rel="nofollow" target="_blank"> Interview with Paul Turner in Current Biology</a> and <a href="https://twitter.com/SteveStuWill/status/1581794682031308800/photo/1" rel="nofollow" target="_blank"> Map of the World if you are a fish</a> Vincent – <a href="https://apps.who.int/iris/handle/10665/39485" rel="nofollow" target="_blank">Smallpox and its eradication</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 84: Decoding our defenses to the Black Death

Florian Maderspacher from Current Biology joins Nels and Vincent to discuss a special issue of the journal on birds. Hosts: Nels Elde and Vincent Racaniello Guest: Florian Maderspacher Subscribe (free): Apple Podcasts,  Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode  Current Biology Birds Special Issue  Scott Edwards bikes across the US (Audubon) Support Diversity Issues in Evolution (Go Fund Me) Time stamps by Jolene. Thanks!  Science Picks Florian – Favorite birds of authors/contributors in Birds issue Nels –Loss of avian intromittent organs as a sperm competition strategy: a race to be last Vincent – Malaria at the Bronx Zoo (TWiP 110) Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Florian Maderspacher from Current Biology joins Nels and Vincent to discuss a special issue of the journal on birds. Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Guest: <a href="https://www.cell.com/current-biology/editors-and-staff" rel="nofollow" target="_blank">Florian Maderspacher</a> Subscribe (free): <a href="https://podcasts.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank">Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank"> Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode <ul> <li>Current Biology <a href="https://www.cell.com/current-biology/current#Birdsspecialissue" rel="nofollow" target="_blank">Birds Special Issue</a></li> <li><a href="https://www.audubon.org/news/journey-complete-scott-edwards-looks-back-his-cross-country-bicycling-trip" rel="nofollow" target="_blank"> Scott Edwards</a> bikes across the US (Audubon)</li> <li>Support <a href="https://www.gofundme.com/f/diversifyevolution" rel="nofollow" target="_blank">Diversity Issues in Evolution</a> (Go Fund Me)</li> <li>Time stamps by <a href="https://twitter.com/jrrmicro" rel="nofollow" target="_blank">Jolene</a>. Thanks!</li> </ul> Science Picks Florian – Favorite birds of authors/contributors in Birds issue Nels –<a href="https://www.journals.uchicago.edu/doi/10.1086/722100" rel="nofollow" target="_blank">Loss of avian intromittent organs as a sperm competition strategy: a race to be last</a> Vincent – Malaria at the Bronx Zoo (<a href="https://www.microbe.tv/twip/twip-110/" rel="nofollow" target="_blank">TWiP 110</a>) Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 83: Evolution spreads its wings (and then loses them)

This Week in Evolution is a podcast on the biology of what makes us tick. Hosts Nels Elde and Vincent Racaniello take you through the new evolution that has been revolutionized by the field of genomics and molecular biology.

I like this show. It’s a painless way to learn.

🐬🌎🦎

You can know what this week in evolution is up to as well as what it was up to in previous weeks.

This Week in Evolution

Nels and Vincent discuss an opinion piece on 12 evolutionary insights into how the COVID-19 pandemic is shaping human nature, and prolonged SARS-CoV-2 reproduction in an immunosuppressed patient. Subscribe (free): iTunes,  Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode  Microbe.TV on instagram Pandemic exposes human nature (PNAS) Carl Bergstrom calls BS (Twitter) Prolonged SARS-CoV-2 reproduction in patient (J Inf Dis) Letters read on TWiEVO 61 Time stamps by Jolene. Thanks!  Science Picks Nels –  Scott Edwards bikes across US; support diversity in evolution Vincent – 30 computers sculpture project Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent discuss an opinion piece on 12 evolutionary insights into how the COVID-19 pandemic is shaping human nature, and prolonged SARS-CoV-2 reproduction in an immunosuppressed patient. Subscribe (free): <a href="https://itunes.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank"> Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Links for this episode <ul> <li><a href="https://www.instagram.com/microbe.tv/" rel="nofollow" target="_blank">Microbe.TV on instagram</a></li> <li>Pandemic exposes <a href="https://www.pnas.org/content/early/2020/10/21/2009787117" rel="nofollow" target="_blank">human nature</a> (PNAS)</li> <li><a href="https://twitter.com/CT_Bergstrom/status/1319424455626485765" rel="nofollow" target="_blank">Carl Bergstrom</a> calls BS (Twitter)</li> <li><a href="https://pubmed.ncbi.nlm.nih.gov/33089317/" rel="nofollow" target="_blank">Prolonged SARS-CoV-2 reproduction</a> in patient (J Inf Dis)</li> <li><a href="https://www.microbe.tv/twievo/twievo-61-letters/" rel="nofollow" target="_blank">Letters read</a> on TWiEVO 61</li> <li>Time stamps by <a href="http://www.twitter.com/jrrmicro" rel="nofollow" target="_blank">Jolene</a>. Thanks!</li> </ul> Science Picks Nels – <a href="https://www.audubon.org/news/journey-complete-scott-edwards-looks-back-his-cross-country-bicycling-trip" rel="nofollow" target="_blank"> Scott Edwards bikes across US</a>; <a href="https://www.gofundme.com/f/diversifyevolution" rel="nofollow" target="_blank">support diversity in evolution</a> Vincent – <a href="http://www.30computers.com/" rel="nofollow" target="_blank">30 computers sculpture project</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 61: Shot and chaser of SARS-CoV-2 evolution

Nels and Vincent dive deep into evolution and consider how new proteins emerged billions of years ago, when there were no other proteins to serve as starting material. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO  Primordial emergence of a nucleic acid binding protein (bioRxiv)  Tawfik laboratory Image credit Letters read on TWiEVO 51 Time stamps by Jolene. Thanks!  Science Picks Nels -  Universal principled review Vincent - Hostile Planet by National Geographic Listener Pick Courtney - Nightwish Endless Forms Most Beautiful and Shudder Before The Beautiful Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent dive deep into evolution and consider how new proteins emerged billions of years ago, when there were no other proteins to serve as starting material. Hosts: <a href="http://cellvolution.org/" rel="noreferrer noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noreferrer noopener nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://itunes.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="noreferrer noopener nofollow" target="_blank">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="noreferrer noopener nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="noreferrer noopener nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="noreferrer noopener nofollow" target="_blank">email</a> <a href="http://www.microbe.tv/contribute" rel="noreferrer noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li>Primordial emergence of a <a href="http://dx.doi.org/10.1101/2020.01.18.911073" rel="nofollow" target="_blank">nucleic acid binding protein</a> (bioRxiv)</li> <li><a href="http://www.weizmann.ac.il/Biomolecular_Sciences/Tawfik/research-activities" rel="nofollow" target="_blank"> Tawfik laboratory</a></li> <li><a href="http://dx.doi.org/10.1101/2020.01.18.911073" rel="nofollow" target="_blank">Image credit</a></li> <li><a href="http://microbe.tv/twievo/twievo-51-letters" rel="nofollow" target="_blank">Letters read</a> on TWiEVO 51</li> <li>Time stamps by <a href="http://www.twitter.com/jrrmicro" rel="nofollow" target="_blank">Jolene</a>. Thanks!</li> </ul> Science Picks Nels - <a href="https://www.sciencedirect.com/science/article/pii/S0092867419312863?via%3Dihub" rel="nofollow" target="_blank"> Universal principled review</a> Vincent - <a href="https://www.outsideonline.com/2393053/hostile-planet-series" rel="nofollow" target="_blank">Hostile Planet by National Geographic</a> Listener Pick Courtney - Nightwish <a href="https://www.youtube.com/watch?v=VUb1p8fm7Ag" rel="nofollow" target="_blank">Endless Forms Most Beautiful</a> and <a href="https://www.youtube.com/watch?v=see_TY5ANEc" rel="nofollow" target="_blank">Shudder Before The Beautiful</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 51: The starting point paradox

On the fifth anniversary of TWiEVO, Nels and Vincent invite 12 evolutionary biologists to describe exciting future directions for the field and their laboratory in the next five years. Hosts: Nels Elde and Vincent Racaniello Guests: Lillian Fritz Laylin, Talia Karasov, Andrew Kern, Sarah Tishkoff, Dmitri Petrov, Nancy Chen, Amanda Larracuente, John McCutcheon, Ambika Kamath, Chip Aquadro, Rebekah Rogers, Yaniv Braindvain, and Harmit Malik Subscribe (free): iTunes,  Google Podcasts, RSS, email Become a patron of TWiEVO Science Picks Nels - Science Mill Virtual Tour and Benefit Vincent - Das Coronavirus summaries Music on TWiEVO is performed by Trampled by Turtles  Send your evolution questions and comments to twievo@microbe.tv

On the fifth anniversary of TWiEVO, Nels and Vincent invite 12 evolutionary biologists to describe exciting future directions for the field and their laboratory in the next five years. Hosts: <a href="http://cellvolution.org/" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Guests: <a href="http://www.fritzlaylinlab.org/" rel="nofollow" target="_blank">Lillian Fritz Laylin</a>, <a href="https://www.tkarasovlab.org/home" rel="nofollow" target="_blank">Talia Karasov</a>, <a href="http://www.kernlab.org/" rel="nofollow" target="_blank">Andrew Kern</a>, <a href="https://www.med.upenn.edu/tishkoff/index.html" rel="nofollow" target="_blank">Sarah Tishkoff</a>, <a href="http://petrov.stanford.edu/" rel="nofollow" target="_blank">Dmitri Petrov</a>, <a href="https://popgenchenlab.github.io/" rel="nofollow" target="_blank">Nancy Chen</a>, <a href="http://blogs.rochester.edu/larracuente/home-2/" rel="nofollow" target="_blank">Amanda Larracuente</a>, <a href="http://mccutcheonlab.org/" rel="nofollow" target="_blank">John McCutcheon</a>, <a href="https://ambikamath.com/" rel="nofollow" target="_blank">Ambika Kamath</a>, <a href="https://www.aquadrolab.com/" rel="nofollow" target="_blank">Chip Aquadro</a>, <a href="http://evolscientist.com/" rel="nofollow" target="_blank">Rebekah Rogers</a>, <a href="https://brandvainlab.wordpress.com/author/yanivbrandvain/" rel="nofollow" target="_blank">Yaniv Braindvain</a>, and <a href="https://research.fhcrc.org/malik/en.html" rel="nofollow" target="_blank">Harmit Malik</a> Subscribe (free): <a href="https://itunes.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="nofollow" target="_blank">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="nofollow" target="_blank"> Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="nofollow" target="_blank">email</a> <a href="https://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO Science Picks Nels - <a href="https://www.sciencemill.org/futureofscience" rel="nofollow" target="_blank">Science Mill Virtual Tour and Benefit</a> Vincent - <a href="https://www.microbe.tv/das-coronavirus/" rel="nofollow" target="_blank">Das Coronavirus summaries</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 60: Five years of TWiEVO on the future of our past

Matt joins Nels and Vincent to discuss the neutral theory of evolution and its rejection in light of genome-scale data. Hosts: Nels Elde and Vincent Racaniello Guest: Matt Hahn Become a patron of TWiEVO  Hahn Lab Molecular Population Genetics by Matt Hahn Neutral theoryin light of natural selection (Mol Biol Evol) Neutral Sequence Fallacy(Assembly of Fragments) Splendor and miseryof adaptation (BMC Biol) Image credit Letters readon TWiEVO 32  Science Picks Nels - Inaugural Transposon Day Vincent - How many human genes? Listener Pick Anne- Plants repeatedly lose ability to obtain nitrogen Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Matt joins Nels and Vincent to discuss the neutral theory of evolution and its rejection in light of genome-scale data. Hosts: <a href="http://cellvolution.org/" rel="noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noopener nofollow" target="_blank">Vincent Racaniello</a> Guest: <a href="http://www.twitter.com/3rdreviewer" rel="noopener nofollow" target="_blank">Matt Hahn</a> <a href="http://www.microbe.tv/contribute" rel="noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li><a href="http://www.indiana.edu/~hahnlab/" rel="noopener nofollow" target="_blank">Hahn Lab</a></li> <li><a href="https://amzn.to/2JOwDAx" rel="noopener nofollow" target="_blank">Molecular Population Genetics</a> by Matt Hahn</li> <li><a href="https://academic.oup.com/mbe/article/35/6/1366/4990884" rel="noopener nofollow" target="_blank">Neutral theory</a>in light of natural selection (Mol Biol Evol)</li> <li>Neutral Sequence <a href="https://caseybergman.wordpress.com/2012/09/09/on-the-neutral-sequence-fallacy/" rel="noopener nofollow" target="_blank">Fallacy</a>(Assembly of Fragments)</li> <li><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180405/" rel="noopener nofollow" target="_blank">Splendor and misery</a>of adaptation (BMC Biol)</li> <li><a href="https://en.wikipedia.org/wiki/Spandrel_(biology)" rel="noopener nofollow" target="_blank">Image credit</a></li> <li><a href="http://microbe.tv/twievo/twievo-32-letters" rel="noopener nofollow" target="_blank">Letters read</a>on TWiEVO 32</li> </ul> Science Picks Nels - <a href="https://mobilednajournal.biomedcentral.com/transposonday2018" rel="noopener nofollow" target="_blank">Inaugural Transposon Day</a> Vincent - <a href="https://www.nature.com/articles/d41586-018-05462-w" rel="noopener nofollow" target="_blank">How many human genes?</a> Listener Pick Anne- <a href="https://arstechnica.com/science/2018/05/plants-repeatedly-got-rid-of-their-ability-to-obtain-their-own-nitrogen/" rel="noopener nofollow" target="_blank">Plants repeatedly lose ability to obtain nitrogen</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 32: Never not neutral

Sarah Tishkoff joins Nels and Vincent to explain work from her laboratory on the genetic basis of skin pigmentation in Africans. Hosts: Nels Elde and Vincent Racaniello Guest: Sarah Tishkoff Become a patron of TWiEVO  Molecular Evolution and the Cell meeting Sarah AMA on Reddit Genetics of African skin pigmentation (Science) Image credit  Science Picks Nels - In Defense of Plants (Shrew Loo) Vincent -  Contribution of NIH funding to new drug approvals Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Sarah Tishkoff joins Nels and Vincent to explain work from her laboratory on the genetic basis of skin pigmentation in Africans. Hosts: <a href="http://cellvolution.org" rel="noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noopener nofollow" target="_blank">Vincent Racaniello</a> Guest: <a href="https://www.med.upenn.edu/tishkoff/index.html" rel="noopener nofollow" target="_blank">Sarah Tishkoff</a> <a href="http://www.microbe.tv/contribute" rel="noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li><a href="https://www.ucegg.org/smbeutah2018" rel="noopener nofollow" target="_blank">Molecular Evolution and the Cell</a> meeting</li> <li>Sarah <a href="https://www.reddit.com/r/science/comments/3mgh26/science_ama_series_i_study_the_population_history/" rel="noopener nofollow" target="_blank">AMA on Reddit</a></li> <li>Genetics of African <a href="https://www.ncbi.nlm.nih.gov/pubmed/29025994" rel="noopener nofollow" target="_blank">skin pigmentation</a> (Science)</li> <li><a href="https://www.med.upenn.edu/tishkoff/index.html" rel="noopener nofollow" target="_blank">Image credit</a></li> </ul> Science Picks Nels - <a href="http://www.indefenseofplants.com" rel="noopener nofollow" target="_blank">In Defense of Plants</a> (<a href="https://www.livescience.com/9666-pitcher-plant-doubles-toilet.html" rel="noopener nofollow" target="_blank">Shre</a><a href="https://www.livescience.com/9666-pitcher-plant-doubles-toilet.html" rel="noopener nofollow" target="_blank">w</a> <a href="https://www.livescience.com/9666-pitcher-plant-doubles-toilet.html" rel="noopener nofollow" target="_blank">Loo</a>) Vincent - <a href="http://www.pnas.org/content/early/2018/02/06/1715368115.short?rss=1" rel="nofollow" target="_blank"> Contribution of NIH funding to new drug approvals</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com" rel="noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 28: Genetics of skin pigmentation in Africa

Nels and Vincent reveal a highly conserved protein that acts as an evolvability factor, increasing mutation and the ability of bacteria to become resistant to antibiotics. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO  Inhibiting evolution of antibiotic resistance (Mol Cell) Pushing viruses over the  error threshold (virology blog) Image credit Letters read on TWiEVO 38  Science Picks Nels- Science/nature illustrator/artist Rachel Ignotofsky (website, Etsy shop) Vincent- Life Ascending by Nick Lane  Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent reveal a highly conserved protein that acts as an evolvability factor, increasing mutation and the ability of bacteria to become resistant to antibiotics. Hosts: <a href="http://cellvolution.org/" rel="noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noopener nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://itunes.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="noopener nofollow" target="_blank">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="noopener nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="noopener nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="noopener nofollow" target="_blank">email</a> <a href="http://www.microbe.tv/contribute" rel="noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li>Inhibiting evolution of <a href="https://www.ncbi.nlm.nih.gov/pubmed/30449724" rel="nofollow" target="_blank">antibiotic resistance</a> (Mol Cell)</li> <li>Pushing viruses over the <a href="http://www.virology.ws/2009/05/14/pushing-viruses-over-the-error-threshold/" rel="nofollow" target="_blank"> error threshold</a> (virology blog)</li> <li><a href="https://faculty.washington.edu/merrikh/" rel="nofollow" target="_blank">Image credit</a></li> <li><a href="http://microbe.tv/twievo/twievo-38-letters" rel="nofollow" target="_blank">Letters read</a> on TWiEVO 38</li> </ul> Science Picks Nels- Science/nature illustrator/artist Rachel Ignotofsky (<a href="https://www.rachelignotofskydesign.com/" rel="nofollow" target="_blank">website</a>, <a href="https://www.etsy.com/shop/Rachelignotofsky" rel="nofollow" target="_blank">Etsy shop</a>) Vincent- <a href="https://amzn.to/2R3CcxS" rel="nofollow" target="_blank">Life Ascending by Nick Lane</a>  Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 38: Evolving to evolve

Hosts: Nels Elde and Vincent Racaniello Nels and Vincent discuss the evolution of recombination in the genomes of birds and yeast. Links for this episode  Stable recombination hotspots in birds (Science) Putting the breaks on meiosis (Science) Evolutionary stability of recombination in yeast (Science) Image credit  Science Picks Nels - Tardigrade horizontal gene transfer (The Atlantic article)Vincent - Einstein's theory of relativity changed everything Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Hosts: <a href="http://cellvolution.org" rel="noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noopener nofollow" target="_blank">Vincent Racaniello</a> Nels and Vincent discuss the evolution of recombination in the genomes of birds and yeast. Links for this episode <ul> <li>Stable <a href="http://www.ncbi.nlm.nih.gov/pubmed/26586757" rel="noopener nofollow" target="_blank">recombination hotspots</a> in birds (Science)</li> <li>Putting the breaks on <a href="http://www.ncbi.nlm.nih.gov/pubmed/26586748" rel="noopener nofollow" target="_blank">meiosis</a> (Science)</li> <li>Evolutionary <a href="http://www.ncbi.nlm.nih.gov/pubmed/26586758" rel="noopener nofollow" target="_blank">stability</a> of recombination in yeast (Science)</li> <li><a href="https://en.wikipedia.org/wiki/Zebra_finch#/media/File:Zebrafinchchicks.jpg" rel="noopener nofollow" target="_blank">Image credit</a></li> </ul> Science Picks Nels - <a href="http://www.pnas.org/content/112/52/15976.abstract" rel="noopener nofollow" target="_blank">Tardigrade horizontal gene transfer</a> (The Atlantic <a href="http://www.theatlantic.com/science/archive/2015/11/tardigrades-worlds-toughest-animals-borrowed-a-sixth-of-their-dna-from-microbes/417243/" rel="noopener nofollow" target="_blank">article</a>)<a href="http://www.sciencedirect.com/science/journal/00426822/466/supp/C" rel="noopener nofollow" target="_blank"></a>Vincent - <a href="http://www.nytimes.com/2015/11/24/science/a-century-ago-einsteins-theory-of-relativity-changed-everything.html?_r=1" rel="noopener nofollow" target="_blank">Einstein's theory of relativity changed everything</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com" rel="noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 3: Recombination is for the birds

Nels and Vincent discuss the evolution of blood feeding to nonbiting in a mosquito, and evolution of bacterial virulence in the house finch caused by incomplete host immunity. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO  Molecular Evolution and the Cell meeting Mosquito evolution from blood feeding to nonbiting (PNAS) Mosquito blood feeding is not a free lunch (virology blog) Incomplete immunity and evolution of virulence (Science) Image credit Letters read on TWiEVO 29  Science Picks Nels - IDEA and Impossible Foods Vincent - it is NOT junk Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent discuss the evolution of blood feeding to nonbiting in a mosquito, and evolution of bacterial virulence in the house finch caused by incomplete host immunity. Hosts: <a href="http://cellvolution.org" rel="noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noopener nofollow" target="_blank">Vincent Racaniello</a> <a href="http://www.microbe.tv/contribute" rel="noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li><a href="https://www.ucegg.org/smbeutah2018" rel="noopener nofollow" target="_blank">Molecular Evolution and the Cell</a> meeting</li> <li>Mosquito evolution from <a href="http://www.pnas.org/content/early/2017/12/14/1717502115" rel="noopener nofollow" target="_blank">blood feeding to nonbiting</a> (PNAS)</li> <li>Mosquito blood feeding is <a href="http://www.virology.ws/2018/03/15/mosquito-blood-feeding-is-not-a-free-lunch/" rel="noopener nofollow" target="_blank">not a free lunch</a> (virology blog)</li> <li>Incomplete immunity and <a href="http://science.sciencemag.org/content/359/6379/1030" rel="noopener nofollow" target="_blank">evolution of virulence</a> (Science)</li> <li><a href="https://commons.wikimedia.org/wiki/File:Haemorhous_mexicanus_(3696885271).jpg" rel="noopener nofollow" target="_blank">Image credit</a></li> <li><a href="http://microbe.tv/twievo/twievo-29-letters" rel="noopener nofollow" target="_blank">Letters read</a> on TWiEVO 29</li> </ul> Science Picks Nels - <a href="https://idea-instructions.com" rel="noopener nofollow" target="_blank">IDEA</a> and <a href="https://www.impossiblefoods.com/" rel="noopener nofollow" target="_blank">Impossible Foods</a> Vincent - <a href="http://www.michaeleisen.org/blog/" rel="noopener nofollow" target="_blank">it is NOT junk</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com" rel="noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 29: Evolution on the wing

Nels and Vincent review the contribution of multiple Denisovan lineages to the modern Papuan genome. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO  Denisovan ancestries in Papuans (Cell) Prof Murray Cox Image credit Letters read on TWiEVO 42 Time stamps by Jolene. Thanks!  Science Picks Nels- Sydney Brenner - What Genomes Can Tell Us About the PastVincent- Scientific Communication in a Post-Truth Society Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent review the contribution of multiple Denisovan lineages to the modern Papuan genome. Hosts: <a href="http://cellvolution.org/" rel="noreferrer noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noreferrer noopener nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://itunes.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="noreferrer noopener nofollow" target="_blank">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="noreferrer noopener nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="noreferrer noopener nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="noreferrer noopener nofollow" target="_blank">email</a> <a href="http://www.microbe.tv/contribute" rel="noreferrer noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li><a href="https://www.ncbi.nlm.nih.gov/pubmed/30981557" rel="nofollow" target="_blank">Denisovan ancestries</a> in Papuans (Cell)</li> <li><a href="https://www.genomicus.com/" rel="nofollow" target="_blank">Prof Murray Cox</a></li> <li><a href="https://en.wikipedia.org/wiki/Denisovan" rel="nofollow" target="_blank">Image credit</a></li> <li><a href="http://microbe.tv/twievo/twievo-42-letters" rel="nofollow" target="_blank">Letters read</a> on TWiEVO 42</li> <li>Time stamps by <a href="http://www.twitter.com/jrrmicro" rel="nofollow" target="_blank">Jolene</a>. Thanks!</li> </ul> Science Picks Nels- <a href="https://www.youtube.com/watch?v=Hhyy4SDEdII&amp;feature=youtu.be" rel="nofollow" target="_blank">Sydney Brenner - What Genomes Can Tell Us About the Past</a>Vincent- <a href="https://www.pnas.org/content/116/16/7656" rel="nofollow" target="_blank">Scientific Communication in a Post-Truth Society</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 42: Who's who in your genome

Nels and Vincent present ancient hepatitis B virus genome sequences from Bronze Age to Medieval period human remains. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO  Ancient hepatitis B virus genomes(Nature) Even more ancient HBV genomes(bioRxiv) Image credit Letters readon TWiEVO 31  Science Picks Nels - Sampling whale breathwith drones (Preprint) Vincent - Verge Science Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent present ancient hepatitis B virus genome sequences from Bronze Age to Medieval period human remains. Hosts: <a href="http://cellvolution.org/" rel="noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noopener nofollow" target="_blank">Vincent Racaniello</a> <a href="http://www.microbe.tv/contribute" rel="noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li>Ancient <a href="http://www.nature.com/articles/s41586-018-0097-z" rel="noopener nofollow" target="_blank">hepatitis B virus genomes</a>(Nature)</li> <li>Even more <a href="https://www.biorxiv.org/content/early/2018/05/06/315531" rel="noopener nofollow" target="_blank">ancient HBV genomes</a>(bioRxiv)</li> <li><a href="https://commons.wikimedia.org/wiki/File:Bronze_age_dwelling_at_Flag_Fen.JPG" rel="noopener nofollow" target="_blank">Image credit</a></li> <li><a href="http://microbe.tv/twievo/twievo-31-letters" rel="noopener nofollow" target="_blank">Letters read</a>on TWiEVO 31</li> </ul> Science Picks Nels - Sampling <a href="https://www.preprints.org/manuscript/201805.0184/v1" rel="noopener nofollow" target="_blank">whale breath</a>with drones (Preprint) Vincent - <a href="https://www.youtube.com/channel/UCtxJFU9DgUhfr2J2bveCHkQ" rel="noopener nofollow" target="_blank">Verge Science</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 31: Virus archaeology, or when the human genome is the junk

Hosts: Nels Elde and Vincent Racaniello Nels visits Vincent in the MicrobeTV studio in New York and talks about how key genes of the Homo sapiens innate immune response were acquired from Neanderthals.   Links for this episode  Introgressed Neanderthal haplotype at OAS locus (biorXiv) Genetic time travel (Genetics) Genetic history of Ice Age Europe (Nature) Letters read on TWiEVO 8  Science Picks Nels - DNA Clues to our Inner Neanderthal Vincent - Blockhead Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv Become a patron of TWiEVO

Hosts: <a href="http://cellvolution.org" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Nels visits Vincent in the MicrobeTV studio in New York and talks about how key genes of the Homo sapiens innate immune response were acquired from Neanderthals.   Links for this episode <ul> <li>Introgressed <a href="http://biorxiv.org/content/early/2016/05/04/051466" rel="nofollow" target="_blank">Neanderthal haplotype</a> at OAS locus (biorXiv)</li> <li>Genetic <a href="http://www.genetics.org/content/203/1/9" rel="nofollow" target="_blank">time travel</a> (Genetics)</li> <li><a href="http://www.nature.com/nature/journal/vaop/ncurrent/full/nature17993.html" rel="nofollow" target="_blank">Genetic history</a> of Ice Age Europe (Nature)</li> <li><a href="http://www.microbe.tv/twieve/twievo-8-letters" rel="nofollow" target="_blank">Letters read</a> on TWiEVO 8</li> </ul> Science Picks Nels - <a href="https://www.ted.com/talks/svante_paeaebo_dna_clues_to_our_inner_neanderthal?language=en#t-9198" rel="nofollow" target="_blank">DNA Clues to our Inner Neanderthal</a> Vincent - <a href="https://tenonedesign.com/blockhead.php" rel="nofollow" target="_blank">Blockhead</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com" rel="nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv <a href="http://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO

TWiEVO 8: Everyone's a little bit Neanderthal

Hosts: Nels Elde and Vincent Racaniello Guest: Nitin Phadnis Nitin joins Nels and Vincent to explain how he identified a gene that is responsible for male inviability in hybrids from a cross between two species of fruit flies. Links for this episode  Cell cycle regulation gene causes hybrid inviability in fruit fly (Science) Phadnis laboratory Phadnis laboratory on Facebook Gene for new species discovered (UNews) Tardigrade HGT disputed (bioRxiv) Photo credit: Lee J. Siegel, University of Utah  Science Picks Nels - Watercolor of Darwin and crewVincent - SpaceX rocket landing (Verge and ArsTechnica) Nitin - 120th anniversary of Roentgen's first X-ray Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Hosts: <a href="http://cellvolution.org" rel="noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noopener nofollow" target="_blank">Vincent Racaniello</a> Guest: Nitin Phadnis Nitin joins Nels and Vincent to explain how he identified a gene that is responsible for male inviability in hybrids from a cross between two species of fruit flies. Links for this episode <ul> <li>Cell cycle regulation gene causes <a href="http://www.ncbi.nlm.nih.gov/pubmed/26680200" rel="noopener nofollow" target="_blank">hybrid inviability</a> in fruit fly (Science)</li> <li><a href="http://flygenetics.com" rel="noopener nofollow" target="_blank">Phadnis laboratory</a></li> <li>Phadnis laboratory on <a href="https://www.facebook.com/PhadnisLab/?fref=nf" rel="noopener nofollow" target="_blank">Facebook</a></li> <li>Gene for new species <a href="http://unews.utah.edu/a-gene-for-new-species-is-discovered/" rel="noopener nofollow" target="_blank">discovered</a> (UNews)</li> <li>Tardigrade HGT <a href="http://biorxiv.org/content/early/2015/12/01/033464" rel="noopener nofollow" target="_blank">disputed</a> (bioRxiv)</li> <li>Photo credit: <a href="http://unews.utah.edu/a-gene-for-new-species-is-discovered/" rel="noopener nofollow" target="_blank">Lee J. Siegel, University of Utah</a></li> </ul> Science Picks Nels - <a href="http://www.sothebys.com/en/auctions/ecatalogue/2014/english-literature-history-childrens-books-illustrations-l15408/lot.10.html" rel="noopener nofollow" target="_blank">Watercolor of Darwin and crew</a><a href="http://www.sciencedirect.com/science/journal/00426822/466/supp/C" rel="noopener nofollow" target="_blank"></a>Vincent - SpaceX rocket landing (<a href="http://www.theverge.com/2015/12/22/10644522/spacex-falcon9-rocket-landing-reaction" rel="noopener nofollow" target="_blank">Verge</a> and <a href="http://arstechnica.com/science/2015/12/by-making-a-historic-landing-spacex-launches-new-age-of-spaceflight/" rel="noopener nofollow" target="_blank">ArsTechnica</a>) Nitin - <a href="https://www.awesomestories.com/asset/view/First-X-ray-1895-Anna-Bertha-Roentgen-s-Hand" rel="noopener nofollow" target="_blank">120th anniversary of Roentgen's first X-ray</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com" rel="noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 4: Taking the mystery out of the mystery of mysteries

Vinny Lynch joins Nels and Vincent to discuss how a zombie gene in elephants protects these large, long lived animals from cancer. Hosts: Nels Elde and Vincent Racaniello Guest: Vinny Lynch   Become a patron of TWiEVO  Lynch Lab Elephant zombie LIF gene induces apoptosis (bioRxiv) Image credit  Science Picks Nels - Animalism Vincent - Voyager I fires up thrusters after 37 years Vinny - Rollin' Wild Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Vinny Lynch joins Nels and Vincent to discuss how a zombie gene in elephants protects these large, long lived animals from cancer. Hosts: <a href="http://cellvolution.org" rel="noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noopener nofollow" target="_blank">Vincent Racaniello</a> Guest: Vinny Lynch <a href="http://www.microbe.tv/contribute" rel="noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li><a href="https://lynchlab.uchicago.edu/" rel="noopener nofollow" target="_blank">Lynch Lab</a></li> <li>Elephant zombie LIF gene <a href="http://dx.doi.org/10.1101/187922" rel="noopener nofollow" target="_blank">induces apoptosis</a> (bioRxiv)</li> <li><a href="https://www.animalbliss.com/rock-hyrax-elephant/" rel="noopener nofollow" target="_blank">Image credit</a></li> </ul> Science Picks Nels - <a href="https://www.facebook.com/AnimalismbyTheAtlantic/?hc_ref=ARRUPsJJyPJ_ZvEO7ODDGWjq6XoaR4onmv2Uk0svG78kbj-QYnWo7ycflR9lCoodvvs" rel="noopener nofollow" target="_blank">Animalism</a> Vincent - <a href="https://www.jpl.nasa.gov/news/news.php?release=2017-310" rel="noopener nofollow" target="_blank">Voyager I fires up thrusters after 37 years</a> Vinny - <a href="http://www.rollinwild.com/" rel="nofollow" target="_blank">Rollin' Wild</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com" rel="noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 26: My Scientist Vinny

Nels and Vincent discuss signatures of sex chromosome evolution revealed by assembly of a young vertebrate Y chromosome from 3-spined stickleback fish. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO  Assembly of a young vertebrate Y chromosome (bioRxiv)  Image credit Letters read on TWiEVO 50 Time stamps by Jolene. Thanks!  Science Picks Nels - Genome from a  5,700-Year-Old Wad of Chewed Gum Vincent -  NJ Sea-Level Rise Reports Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent discuss signatures of sex chromosome evolution revealed by assembly of a young vertebrate Y chromosome from 3-spined stickleback fish. Hosts: <a href="http://cellvolution.org/" rel="noreferrer noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noreferrer noopener nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://itunes.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="noreferrer noopener nofollow" target="_blank">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="noreferrer noopener nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="noreferrer noopener nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="noreferrer noopener nofollow" target="_blank">email</a> <a href="http://www.microbe.tv/contribute" rel="noreferrer noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li>Assembly of a young vertebrate <a href="https://dx.doi.org/10.1101/2019.12.12.874701" rel="nofollow" target="_blank">Y chromosome</a> (bioRxiv)</li> <li><a href="https://en.wikipedia.org/wiki/Three-spined_stickleback#/media/File:Gasterosteus_aculeatus_1879.jpg" rel="nofollow" target="_blank"> Image credit</a></li> <li><a href="http://microbe.tv/twievo/twievo-50-letters" rel="nofollow" target="_blank">Letters read</a> on TWiEVO 50</li> <li>Time stamps by <a href="http://www.twitter.com/jrrmicro" rel="nofollow" target="_blank">Jolene</a>. Thanks!</li> </ul> Science Picks Nels - Genome from a <a href="https://www.nytimes.com/2019/12/17/science/ancient-gum-dna.html?searchResultPosition=1" rel="nofollow" target="_blank"> 5,700-Year-Old Wad of Chewed Gum</a> Vincent - <a href="https://climatechange.rutgers.edu/resources/climate-change-and-new-jersey/nj-sea-level-rise-reports" rel="nofollow" target="_blank"> NJ Sea-Level Rise Reports</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 50: I'm dreaming of a Y chromosome

Nels and Vincent reveal how a motor protein in corn causes preferential transmission of chromosomes to egg cells, leading to non-Mendelian inheritance. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO  Molecular Evolution and the Cellmeeting Selfishcorn chromosomes (Cell) Dawe Lab- neocentromeres and meiotic drive Image credit Letters readon TWiEVO 30  Science Picks Nels - Craypot stinkhorn mushroom (Colus pusilus) Vincent -Doubts raised over plan to release herpesvirus to wipe out carp Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent reveal how a motor protein in corn causes preferential transmission of chromosomes to egg cells, leading to non-Mendelian inheritance. Hosts: <a href="http://cellvolution.org/" rel="noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noopener nofollow" target="_blank">Vincent Racaniello</a> <a href="http://www.microbe.tv/contribute" rel="noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li><a href="https://www.ucegg.org/smbeutah2018" rel="noopener nofollow" target="_blank">Molecular Evolution and the Cell</a>meeting</li> <li><a href="https://www.sciencedirect.com/science/article/pii/S0092867418302897?via%3Dihub" rel="noopener nofollow" target="_blank">Selfish</a>corn chromosomes (Cell)</li> <li><a href="http://www.dawelab.org/neocentromeres-meiotic-drive" rel="noopener nofollow" target="_blank">Dawe Lab</a>- neocentromeres and meiotic drive</li> <li><a href="https://www.rareseeds.com/glass-gem-corn-/" rel="noopener nofollow" target="_blank">Image credit</a></li> <li><a href="http://microbe.tv/twievo/twievo-30-letters" rel="noopener nofollow" target="_blank">Letters read</a>on TWiEVO 30</li> </ul> Science Picks Nels - <a href="https://en.wikipedia.org/wiki/Colus_pusillus" rel="noopener nofollow" target="_blank">Craypot stinkhorn mushroom (Colus pusilus)</a> Vincent -<a href="https://www.nature.com/articles/d41586-018-02315-4" rel="noopener nofollow" target="_blank">Doubts raised over plan to release herpesvirus to wipe out carp</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 30: Driving Miss Maize-y

Hosts: Nels Elde and Vincent Racaniello Nels and Vincent continue with an emerging sub-theme of TWiEVO - organisms with wings - as they reveal how enhancer shuffling produces diverse butterfly wing patterns.  Links for this episode Enhancer shuffling for butterfly wing patterns (PLoS Biol) Batesian mimicry (Wikipedia) Müllerian mimicry (Wikipedia) Image credit Letters read on TWiEVO 6Science PicksNels - Hill Country Science MillVincent - The Butterfly ConservatoryListener PickStephen - Darwin Legacy Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Hosts: <a href="http://cellvolution.org" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Nels and Vincent continue with an emerging sub-theme of TWiEVO - organisms with wings - as they reveal how enhancer shuffling produces diverse butterfly wing patterns.  Links for this episode <ul> <li><a href="http://www.ncbi.nlm.nih.gov/pubmed/26771987" rel="nofollow" target="_blank">Enhancer shuffling</a> for butterfly wing patterns (PLoS Biol)</li> <li><a href="https://en.wikipedia.org/wiki/Batesian_mimicry" rel="nofollow" target="_blank">Batesian</a> mimicry (Wikipedia)</li> <li><a href="https://en.wikipedia.org/wiki/Müllerian_mimicry" rel="nofollow" target="_blank">Müllerian</a> mimicry (Wikipedia)</li> <li><a href="http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002353" rel="nofollow" target="_blank">Image credit</a></li> <li><a href="http://www.microbe.tv/twievo/twievo-6-letters/" rel="nofollow" target="_blank">Letters read</a> on TWiEVO 6</li></ul>Science Picks Nels - <a href="http://www.sciencemill.org" rel="nofollow" target="_blank">Hill Country Science Mill</a><a href="http://www.sciencedirect.com/science/journal/00426822/466/supp/C" rel="nofollow" target="_blank"></a>Vincent - <a href="http://www.amnh.org/exhibitions/the-butterfly-conservatory" rel="nofollow" target="_blank">The Butterfly Conservatory</a>Listener Pick Stephen - <a href="https://itunes.apple.com/us/itunes-u/darwins-legacy/id384233220?mt=10" rel="nofollow" target="_blank">Darwin Legacy</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com" rel="nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 6: Butterflies are free to shuffle

Nels and Vincent are astounded by the finding of an insect-derived virus in a fungus that manipulates the behavior of flies. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO  Virus in fungus in fly (bioRxiv) On a leaf, no one can hear you scream (TWiV 443) Nels gives Benzer Lecture (YouTube) Domestication of fungal fly pathogen (bioRxiv) Sequencing E. muscae genome (10X genomics) Eisen's twitter stream on new iflavirus (Twitter)  Science Picks Nels - Mindsuckers; getting photos; Anand Varma photos  Vincent - Happy Birthday Gregor Mendel Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent are astounded by the finding of an insect-derived virus in a fungus that manipulates the behavior of flies. Hosts: <a href="http://cellvolution.org/" rel="noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noopener nofollow" target="_blank">Vincent Racaniello</a> <a href="http://www.microbe.tv/contribute" rel="noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li><a href="https://www.biorxiv.org/content/early/2018/07/18/371526" rel="noopener nofollow" target="_blank">Virus in fungus in fly</a> (bioRxiv)</li> <li>On a leaf, no one can hear you scream (<a href="http://www.microbe.tv/twiv/twiv-443/" rel="noopener nofollow" target="_blank">TWiV 443</a>)</li> <li>Nels gives <a href="https://www.youtube.com/watch?v=bblbWo2rmHw&amp;t=166s" rel="noopener nofollow" target="_blank">Benzer Lecture</a> (YouTube)</li> <li>Domestication of <a href="https://www.biorxiv.org/content/biorxiv/early/2017/12/10/232140.full.pdf" rel="noopener nofollow" target="_blank">fungal fly pathogen</a> (bioRxiv)</li> <li>Sequencing <a href="https://community.10xgenomics.com/t5/10x-Blog/Genome-assembly-of-the-mind-controlling-fly-pathogen-E-muscae/ba-p/475" rel="noopener nofollow" target="_blank">E. muscae genome</a> (10X genomics)</li> <li>Eisen's twitter stream on <a href="https://twitter.com/mbeisen/status/1019655132940627969" rel="noopener nofollow" target="_blank">new iflavirus</a> (Twitter)</li> </ul> Science Picks Nels - <a href="https://www.nationalgeographic.com/magazine/2014/11/mindsuckers/" rel="noopener nofollow" target="_blank">Mindsuckers</a>; <a href="https://video.nationalgeographic.com/video/141031-mindsuckers-pictures" rel="noopener nofollow" target="_blank">getting photos</a>; <a href="http://www.varmaphoto.com/mindsuckers/" rel="noopener nofollow" target="_blank">Anand Varma photos</a>  Vincent - <a href="https://www.britannica.com/biography/Gregor-Mendel" rel="noopener nofollow" target="_blank">Happy Birthday Gregor Mendel</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 33: Fly by virus

Rich joins Nels and Vincent for a debriefing on the 4th Ringberg Symposium on Giant Virus Biology in Tegernsee, Germany. Hosts: Nels Elde and Vincent Racaniello Guest:  Rich Condit Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO  Endless giant virus forms most beautiful (TWiV 575)  4th Ringberg Giant Virus Meeting Program (pdf) Photographs by Matthias Fischer Time stamps by Jolene. Thanks!  Science Picks Rich - Flightradar24 Nels - Deutsches Museum Munich Vincent - Diversify Microbiology Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Rich joins Nels and Vincent for a debriefing on the 4th Ringberg Symposium on Giant Virus Biology in Tegernsee, Germany. Hosts: <a href="http://cellvolution.org/" rel="noreferrer noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noreferrer noopener nofollow" target="_blank">Vincent Racaniello</a> Guest: <a href="http://www.mgm.ufl.edu/faculty/faculty-home-pages/condit-richard-c/" rel="nofollow" target="_blank"> Rich Condit</a> Subscribe (free): <a href="https://itunes.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="noreferrer noopener nofollow" target="_blank">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="noreferrer noopener nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="noreferrer noopener nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="noreferrer noopener nofollow" target="_blank">email</a> <a href="http://www.microbe.tv/contribute" rel="noreferrer noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li>Endless giant virus forms most beautiful (<a href="http://www.microbe.tv/twiv/twiv-575/" rel="nofollow" target="_blank">TWiV 575</a>)</li> <li><a href="https://www.mr.mpg.de/14407449/4th-Giant-Virus-Symposium-Program.pdf" rel="nofollow" target="_blank"> 4th Ringberg Giant Virus Meeting Program (pdf)</a></li> <li>Photographs by <a href="http://twitter.com/the_fischer_lab" rel="nofollow" target="_blank">Matthias Fischer</a></li> <li>Time stamps by <a href="http://www.twitter.com/jrrmicro" rel="nofollow" target="_blank">Jolene</a>. Thanks!</li> </ul> Science Picks Rich - <a href="https://www.flightradar24.com/" rel="nofollow" target="_blank">Flightradar24</a> Nels - <a href="https://www.deutsches-museum.de/en/information/" rel="nofollow" target="_blank">Deutsches Museum Munich</a> Vincent - <a href="https://diversifymicrobiology.github.io/" rel="nofollow" target="_blank">Diversify Microbiology</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 49: A giant podcast on giant viruses

Hosts: Nels Elde and Vincent Racaniello Guest: Jim Bull Nels and Vincent speak with Jim Bull about the results of genetic models which suggest that the evolution of inbreeding in response to lethal gene drive might make population control difficult to achieve.   Links for this episode  Lethal gene drive selects inbreeding (bioRxiv) Panel endorses gene drive technology (NY Times) Genes in Conflict by Austin Burt Letters read on TWiEVO 9  Science Picks Nels - Fertilization with parasitic sperm Vincent - Undark Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv Become a patron of TWiEVO

Hosts: <a href="http://cellvolution.org" rel="nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="nofollow" target="_blank">Vincent Racaniello</a> Guest: <a href="https://www.biosci.utexas.edu/directory/details.aspx?id=18" rel="nofollow" target="_blank">Jim Bull</a> Nels and Vincent speak with Jim Bull about the results of genetic models which suggest that the evolution of inbreeding in response to lethal gene drive might make population control difficult to achieve.   Links for this episode <ul> <li>Lethal gene drive <a href="http://biorxiv.org/content/early/2016/06/03/046847" rel="nofollow" target="_blank">selects inbreeding</a> (bioRxiv)</li> <li>Panel endorses <a href="http://www.nytimes.com/2016/06/09/science/national-academies-sciences-gene-drive-technology.html?smid=tw-share&amp;_r=1" rel="nofollow" target="_blank">gene drive</a> technology (NY Times)</li> <li><a href="http://amzn.to/28Q0hxT" rel="nofollow" target="_blank">Genes in Conflict</a> by Austin Burt</li> <li><a href="http://www.microbe.tv/twievo/twievo-9-letters" rel="nofollow" target="_blank">Letters read</a> on TWiEVO 9</li> </ul> Science Picks Nels - <a href="http://blogs.discovermagazine.com/notrocketscience/2011/07/15/hermaphrodite-insects-fertilise-daughters-with-parasitic-sperm/#.V1b8cGN__ZY" rel="nofollow" target="_blank">Fertilization with parasitic sperm</a> Vincent - <a href="http://undark.org/" rel="nofollow" target="_blank">Undark</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com" rel="nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv <a href="http://www.microbe.tv/contribute" rel="nofollow" target="_blank">Become a patron</a> of TWiEVO

TWiEVO 9: How to crash your gene drive

Nels and Vincent examine SARS-CoV-2 from an evolutionary viewpoint, examining what the spike glycoprotein sequence informs us about the origin of the virus. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO  Distinct  CoV name needed (Lancet) Proximal origin of SARS-COV-2 (virological)  CoV spillovers not rare (Goats and Soda) SARS-CoV-2  phylodynamics analysis (virological) Bat CoV surveillance in China (PLoS Path) Image credit Time stamps by Jolene. Thanks!  Science Picks Nels -  Alejandro Sanchez TED Talk Vincent -  WHO SARS-CoV-2 Sitrep Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent examine SARS-CoV-2 from an evolutionary viewpoint, examining what the spike glycoprotein sequence informs us about the origin of the virus. Hosts: <a href="http://cellvolution.org/" rel="noreferrer noopener nofollow" target="_blank">Nels Elde</a> and <a href="http://en.wikipedia.org/wiki/Vincent_Racaniello" rel="noreferrer noopener nofollow" target="_blank">Vincent Racaniello</a> Subscribe (free): <a href="https://itunes.apple.com/us/podcast/this-week-in-evolution/id1067573465" rel="noreferrer noopener nofollow" target="_blank">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aWV2by5saWJzeW4uY29tL3Jzcw%3D%3D" rel="noreferrer noopener nofollow" target="_blank">Google Podcasts</a>, <a href="http://twievo.libsyn.com/rss" rel="noreferrer noopener nofollow" target="_blank">RSS</a>, <a href="http://eepurl.com/Gcw59" rel="noreferrer noopener nofollow" target="_blank">email</a> <a href="http://www.microbe.tv/contribute" rel="noreferrer noopener nofollow" target="_blank">Become a patron</a> of TWiEVO <ul> <li>Distinct <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30419-0/fulltext" rel="nofollow" target="_blank"> CoV name</a> needed (Lancet)</li> <li><a href="http://virological.org/t/the-proximal-origin-of-sars-cov-2/398" rel="nofollow" target="_blank">Proximal origin</a> of SARS-COV-2 (virological)</li> <li><a href="https://www.npr.org/sections/goatsandsoda/2020/02/20/807742861/new-research-bats-harbor-hundreds-of-coronaviruses-and-spillovers-arent-rare" rel="nofollow" target="_blank"> CoV spillovers</a> not rare (Goats and Soda)</li> <li>SARS-CoV-2 <a href="http://virological.org/t/phylodynamic-analysis-129-genomes-24-feb-2020/356" rel="nofollow" target="_blank"> phylodynamics analysis</a> (virological)</li> <li><a href="https://www.ncbi.nlm.nih.gov/pubmed/29190287" rel="nofollow" target="_blank">Bat CoV surveillance</a> in China (PLoS Path)</li> <li><a href="http://virological.org/t/the-proximal-origin-of-sars-cov-2/398" rel="nofollow" target="_blank">Image credit</a></li> <li>Time stamps by <a href="http://www.twitter.com/jrrmicro" rel="nofollow" target="_blank">Jolene</a>. Thanks!</li> </ul> Science Picks Nels - <a href="https://www.ted.com/talks/alejandro_sanchez_alvarado_to_solve_old_problems_study_new_species" rel="nofollow" target="_blank"> Alejandro Sanchez TED Talk</a> Vincent - <a href="https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports" rel="nofollow" target="_blank"> WHO SARS-CoV-2 Sitrep</a> Music on TWiEVO is performed by <a href="http://trampledbyturtles.com/" rel="noreferrer noopener nofollow" target="_blank">Trampled by Turtles</a> Send your evolution questions and comments to twievo@microbe.tv

TWiEVO 52: Virus evolution by land and by sea and by CoV

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