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Immune

A podcast about the body's defenders against disease.

Ranked #1

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Immune 12: Systems immunology

Immune 12: Systems immunology

The Immune trifecta explores systems immunology, and its use in a study of immune system development in newborn children... Read more

19 Sep 2018

1hr 11mins

Ranked #2

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Immune 4: Putting the immunotherapy CAR T before the cancer

Immune 4: Putting the immunotherapy CAR T before the cancer

The immu-knowledge-ists deconstruct the holy grail of oncologists, cancer immunotherapy, and the exciting development of... Read more

23 Jan 2018

1hr 23mins

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Ranked #3

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Immune 3: Two epitopes, four serotypes, and a partridge in a pear tree

Immune 3: Two epitopes, four serotypes, and a partridge in a pear tree

Cindy, Steph, and Vincent discuss recent problems with dengue virus vaccine, and a bi-specific monoclonal antibody again... Read more

16 Dec 2017

1hr 19mins

Ranked #4

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Immune 14: Braking bad

Immune 14: Braking bad

The Immune team explains the science behind the 2018 Nobel Prizes awarded to Allison and Honjo: checkpoint immunotherapy... Read more

14 Nov 2018

1hr 20mins

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Ranked #5

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Immune 8: Staying warm with γδ T cells

Immune 8: Staying warm with γδ T cells

The Immune team reveals how γδ T cells that synthesize interleukin-17A regulate adipose regulatory T cell homeostasis an... Read more

25 May 2018

1hr 19mins

Ranked #6

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Immune 15: Happy neu-trophil year

Immune 15: Happy neu-trophil year

Stephanie takes the Immune team on a tour of neutrophils, the most abundant leukocytes in mammals, including tethers and... Read more

22 Dec 2018

1hr 26mins

Ranked #7

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Immune 26: Measles erases immune memory

Immune 26: Measles erases immune memory

Michael Mina joins the Immune team to explain his findings that measles diminishes pre-existing antibodies that protect ... Read more

28 Nov 2019

1hr 37mins

Ranked #8

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Immune 5: Mother knows best about food allergies

Immune 5: Mother knows best about food allergies

The ImmuoModulators provide a primer on mucosal defenses, and explain how sensitizing female mice to food allergens prev... Read more

22 Feb 2018

1hr 40mins

Ranked #9

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Immune 6: Potent antiviral antibodies without somatic mutation

Immune 6: Potent antiviral antibodies without somatic mutation

The Immune hosts explain how antibody molecules mature, then discuss the finding in infants of potent neutralizing antib... Read more

16 Mar 2018

1hr 29mins

Ranked #10

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Immune 9: Neither mice nor lamprey lie

Immune 9: Neither mice nor lamprey lie

The Immune team explores the variable lymphocyte receptors of jawless vertebrates, a system of immunity that parallels t... Read more

20 Jun 2018

1hr 35mins

Ranked #11

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Immune 25: Remembrance of antigen encounters past

Immune 25: Remembrance of antigen encounters past

The Immune team explains that short chain fatty acids produced by microbial fermentation of fiber rewire metabolism to e... Read more

1 Nov 2019

1hr 22mins

Ranked #12

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Immune 17: Feed a macrophage, starve a tumor

Immune 17: Feed a macrophage, starve a tumor

The immunophiles explain how metabolic rewiring of macrophages by CpG promotes clearance of cancer cells. Hosts: Vincent... Read more

13 Feb 2019

1hr 8mins

Ranked #13

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Immune 7: Contradictory complements in Alzheimer's disease

Immune 7: Contradictory complements in Alzheimer's disease

The Immune hosts discuss how the complement system functions, and its role in early synapse loss in a mouse model of Alz... Read more

18 Apr 2018

1hr 13mins

Ranked #14

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Immune 18: Biting off more TCR than you can chew

Immune 18: Biting off more TCR than you can chew

The immunophiles discuss T cell antigen discovery by trogocytosis - the transfer of membrane patches among cells in clos... Read more

27 Mar 2019

1hr 20mins

Ranked #15

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Immune 22: Engineering B cells

Immune 22: Engineering B cells

Immune reveals an alternative to a protective vaccine, engineered B cells that produce antiviral antibodies. Hosts: Vinc... Read more

31 Jul 2019

1hr 18mins

Ranked #16

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Immune 11: Immunomimetic designer cells

Immune 11: Immunomimetic designer cells

Cindy and Vincent describe the construction of a gene network that programs mammalian cells to detect and eliminate bact... Read more

18 Aug 2018

1hr 8mins

Ranked #17

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Immune 10: Immune goes viral

Immune 10: Immune goes viral

The Immune team travels to the University of Maryland for ASV 2018, where they meet up with Rebecca Lynch to explore her... Read more

21 Jul 2018

1hr 15mins

Ranked #18

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Immune 16: B is for Bursa

Immune 16: B is for Bursa

The Immune team turns to chickens, which have been important in understanding the immune system, to show that infection ... Read more

19 Jan 2019

1hr 12mins

Ranked #19

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Immune 24: Unlucky IL-13

Immune 24: Unlucky IL-13

The Immune team reveals a new type of T helper cell that drives the production of IgE, leading to allergic responses. Ho... Read more

19 Sep 2019

1hr 29mins

Ranked #20

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Immune 21: Islets of Langelhans

Immune 21: Islets of Langelhans

Immune tackles the finding that patients with Type I diabetes have lymphocytes with both TCR and BCR that may drive the ... Read more

12 Jun 2019

1hr 27mins

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