Zev Williams's guest appearances

Zev Williams

Fertile Minds Radio

Lily Nichols

Michelle Gale

Adriana Lozada

Parijat Deshpande

Felice Gersh

Heidi Brockmyre

Denise Wiesner

Jennifer Summerfeldt

Sharna Langlais

Kate Webster

Erin Gray

Katelyn Fusco

Jennifer Horton

Shauna Wetenkamp

Paul Turek

OwlTail

In honor of Recurrent Pregnancy and Infant Loss Awareness month we offer you this wisdom packed episode with Dr. Zev Williams.  If you or someone you know has experienced a miscarriage you owe it to yourself to have a listen. 

In honor of Recurrent Pregnancy and Infant Loss Awareness month we offer you this wisdom packed episode with Dr. Zev Williams.  If you or someone you know has experienced a miscarriage you owe it to yourself to have a listen.

Treating Recurrent Pregnancy Loss with Dr. Zev Williams

Today’s episode features Zev Williams, M.D., Ph.D. He is the Chief of the Division of Reproductive Endocrinology and Infertility and an Associate Professor of Obstetrics and Gynecology at Columbia University Medical Center and is a nationally-recognized clinician and researcher in the area of recurrent pregnancy loss and infertility. Not only is he one of the most brilliant minds I’ve had the pleasure of interviewing, he is incredibly humble, gracious, and passionate about his work. His intentions to help couples overcome recurrent pregnancy loss by building healthy happy families came through so clearly during this chat.   We touched on why miscarriage rates are so high and why the public has false perceptions about it being a rare event. He spoke about how his research has even uncovered a way to find out if the cause of a miscarriage was chromosomal even years after the fact in some cases. He explained the differences in PGD and PGS testing when using IVF and when and for whom it might be highly beneficial. We also spoke about MTHFR gene mutation, and what it really means in regards to treatment strategy and further testing. We even touched on his work with stem cells and the potential they have for one day helping women who experience premature ovarian failure to overcome this devastating diagnosis. He explained new ways to treat endometriosis and preserve fertility and new ways to diagnose PCOS.   To share your own fertility story, please email me at hillary@ladypotions.com. I look forward to connecting with you, as you are what this podcast is all about.   Takeaway: [1:15] Dr. Williams completed his M.D. and Ph.D. training in Molecular Biology and Biochemistry at the Mount Sinai School of Medicine before continuing to the Brigham and Women’s Hospital/Massachusetts General Hospital for his residency in Obstetrics and Gynecology. After completing his fellowship in Reproductive Endocrinology and Infertility at Weill Cornell, Dr. Williams then did a post-doctoral fellowship in RNA biology in the laboratory of Dr. Thomas Tuschl at Rockefeller University. [1:45] Dr. Williams has also achieved success in federally-funded research projects in several different areas of study, having received numerous NIH grants to support his work. Currently, as part of an NIH R01 grant, Dr. Williams is engaged with a research project intended to use placental RNA as a screening tool for diseases and complications of pregnancy, to enable early intervention, and to provide insights into disease pathogenesis for things like pre-eclampsia. [4:35] Dr. Williams works with couples and doctors all over the world, and the research that he and his colleagues find benefits those all over looking for answers on fertility. [5:16] The PEARL Program that Dr. Williams started stands for Program for Early and Recurrent Pregnancy Loss. It is one of the only centers in the world that is both clinically focused, and a basic/translational research program dedicated trying to understand what causes unexplained miscarriages and trying to find ways methods to prevent them in the future. [12:22] One of the realities of human reproduction is that is a very inefficient process. Of the eggs that get fertilized, very few result in a live birth. [19:22] Dr. Williams explains the difference between PGD and PGS testing when using IVF, and who may benefit from these tests. [26:54] We cover the MTHFR gene mutation, and what it really means in regards to treatment, strategy, and further testing. [32:45] Dr. Williams explains the work on helping the brain to produce its own FSH (follicle stimulating hormones) which is the bodies own version of that hormone compared to traditional injections. [41:23] Dr. Williams shares the new ways to treat endometriosis and preserve fertility and new ways to diagnose PCOS. [45:27] Diet is, of course, important to overall health, but also very important to pregnancy success. There are some factors that lead to Dr. Williams’ recommending a diet low in carbs and sugar. [46:12] Egg freezing has become successful, but the challenge is that women are freezing their eggs in their 40’s when the eggs have already lowered in quality. [49:58] Once you are trying to conceive (and of course through all of the process), make sure to support each other. It’s a tough journey and you want to be going through it together.   References: Fertile Minds on LibSyn  Fertile Minds on iTunes American Board of Oriental Reproductive Medicine  Dr. Zev Williams Dr. Zev Williams Bio Columbia University Department of Obstetrics and Gynecology    Efficient Differentiation of Steroidogenic and Germ-Like Cells from Epigenetically Related iPSCs Derived from Ovarian Granulosa Cells  FMR1 targets distinct mRNA sequence elements to regulate protein expression  Nytimes.com/2015/11/26/health/progesterone-may-not-help-women-with-history-of-miscarriages-study-finds  Huffingtonpost.com/science-of-us/miscarriage_b_8000760.html?ncid=txtlnkusaolp00000592  Wsj.com/articles/solving-the-mystery-of-miscarriages-1434389396  Columbiaobgyn.org/profile/s-zev-williams-md Ncbi.nlm.nih.gov/pubmed/26000502  Nyp.org/enewsletters/advances/2018/gynecology/2018-Advances-Gynecology-Issue1.html   Continue Your Journey: Link to sign up for free 29-day meditation challenge @ladypotions4u on Twitter @ladypotions4u on Instagram My Website: Ladypotions.com Special Thanks to Christopher Lloyd Clarke for music   Disclaimer * (please include on all iTunes descriptions and show notes) You must not rely on the information in this podcast as an alternative to medical advice from your doctor or other professional healthcare provider. If you have any specific questions about any medical matter you should consult your doctor or other professional healthcare provider. If you think you may be suffering from any medical condition you should seek immediate medical attention. You should never delay seeking medical advice, disregard medical advice, or discontinue medical treatment because of information on this website or in this podcast.

Today’s episode features Zev Williams, M.D., Ph.D. He is the Chief of the Division of Reproductive Endocrinology and Infertility and an Associate Professor of Obstetrics and Gynecology at Columbia University Medical Center and is a nationally-recognized clinician and researcher in the area of recurrent pregnancy loss and infertility. Not only is he one of the most brilliant minds I’ve had the pleasure of interviewing, he is incredibly humble, gracious, and passionate about his work. His intentions to help couples overcome recurrent pregnancy loss by building healthy happy families came through so clearly during this chat. We touched on why miscarriage rates are so high and why the public has false perceptions about it being a rare event. He spoke about how his research has even uncovered a way to find out if the cause of a miscarriage was chromosomal even years after the fact in some cases. He explained the differences in PGD and PGS testing when using IVF and when and for whom it might be highly beneficial. We also spoke about MTHFR gene mutation, and what it really means in regards to treatment strategy and further testing. We even touched on his work with stem cells and the potential they have for one day helping women who experience premature ovarian failure to overcome this devastating diagnosis. He explained new ways to treat endometriosis and preserve fertility and new ways to diagnose PCOS. To share your own fertility story, please email me at <a href="mailto:hillary@ladypotions.com">hillary@ladypotions.com</a>. I look forward to connecting with you, as you are what this podcast is all about. Takeaway: [1:15] Dr. Williams completed his M.D. and Ph.D. training in Molecular Biology and Biochemistry at the Mount Sinai School of Medicine before continuing to the Brigham and Women’s Hospital/Massachusetts General Hospital for his residency in Obstetrics and Gynecology. After completing his fellowship in Reproductive Endocrinology and Infertility at Weill Cornell, Dr. Williams then did a post-doctoral fellowship in RNA biology in the laboratory of Dr. Thomas Tuschl at Rockefeller University. [1:45] Dr. Williams has also achieved success in federally-funded research projects in several different areas of study, having received numerous NIH grants to support his work. Currently, as part of an NIH R01 grant, Dr. Williams is engaged with a research project intended to use placental RNA as a screening tool for diseases and complications of pregnancy, to enable early intervention, and to provide insights into disease pathogenesis for things like pre-eclampsia. [4:35] Dr. Williams works with couples and doctors all over the world, and the research that he and his colleagues find benefits those all over looking for answers on fertility. [5:16] The PEARL Program that Dr. Williams started stands for Program for Early and Recurrent Pregnancy Loss. It is one of the only centers in the world that is both clinically focused, and a basic/translational research program dedicated trying to understand what causes unexplained miscarriages and trying to find ways methods to prevent them in the future. [12:22] One of the realities of human reproduction is that is a very inefficient process. Of the eggs that get fertilized, very few result in a live birth. [19:22] Dr. Williams explains the difference between PGD and PGS testing when using IVF, and who may benefit from these tests. [26:54] We cover the MTHFR gene mutation, and what it really means in regards to treatment, strategy, and further testing. [32:45] Dr. Williams explains the work on helping the brain to produce its own FSH (follicle stimulating hormones) which is the bodies own version of that hormone compared to traditional injections. [41:23] Dr. Williams shares the new ways to treat endometriosis and preserve fertility and new ways to diagnose PCOS. [45:27] Diet is, of course, important to overall health, but also very important to pregnancy success. There are some factors that lead to Dr. Williams’ recommending a diet low in carbs and sugar. [46:12] Egg freezing has become successful, but the challenge is that women are freezing their eggs in their 40’s when the eggs have already lowered in quality. [49:58] Once you are trying to conceive (and of course through all of the process), make sure to support each other. It’s a tough journey and you want to be going through it together. References: <a href="http://ladypotions.libsyn.com/website/2017/10" rel="nofollow" target="_blank">Fertile Minds on LibSyn</a> <a href="https://itunes.apple.com/us/podcast/fertile-minds-radio/id1291610234?mt=2" rel="nofollow" target="_blank"> Fertile Minds on iTunes</a> <a href="http://www.aborm.org/" rel="nofollow" target="_blank">American Board of Oriental Reproductive Medicine</a> <a href="http://columbiafertility.org/team-members/s-zev-williams-md-phd/#.Wt_9nejwbrc" rel="nofollow" target="_blank"> Dr. Zev Williams</a> <a href="https://www.youtube.com/watch?v=xo-U6B4u6S8" rel="nofollow" target="_blank">Dr. Zev Williams Bio</a> <a href="http://columbiafertility.org/" rel="nofollow" target="_blank">Columbia University Department of Obstetrics and Gynecology  </a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353623/" rel="nofollow" target="_blank"> Efficient Differentiation of Steroidogenic and Germ-Like Cells from Epigenetically Related iPSCs Derived from Ovarian Granulosa Cells</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528815/" rel="nofollow" target="_blank"> FMR1 targets distinct mRNA sequence elements to regulate protein expression</a> <a href="https://www.nytimes.com/2015/11/26/health/progesterone-may-not-help-women-with-history-of-miscarriages-study-finds.html" rel="nofollow" target="_blank"> Nytimes.com/2015/11/26/health/progesterone-may-not-help-women-with-history-of-miscarriages-study-finds</a> <a href="https://www.huffingtonpost.com/science-of-us/miscarriage_b_8000760.html?ncid=txtlnkusaolp00000592" rel="nofollow" target="_blank"> Huffingtonpost.com/science-of-us/miscarriage_b_8000760.html?ncid=txtlnkusaolp00000592</a> <a href="https://www.wsj.com/articles/solving-the-mystery-of-miscarriages-1434389396" rel="nofollow" target="_blank"> Wsj.com/articles/solving-the-mystery-of-miscarriages-1434389396</a> <a href="https://www.columbiaobgyn.org/profile/s-zev-williams-md" rel="nofollow" target="_blank"> Columbiaobgyn.org/profile/s-zev-williams-md</a> <a href="https://www.ncbi.nlm.nih.gov/pubmed/26000502" rel="nofollow" target="_blank">Ncbi.nlm.nih.gov/pubmed/26000502</a> <a href="https://www.nyp.org/enewsletters/advances/2018/gynecology/2018-Advances-Gynecology-Issue1.html" rel="nofollow" target="_blank"> Nyp.org/enewsletters/advances/2018/gynecology/2018-Advances-Gynecology-Issue1.html</a> Continue Your Journey: <a href="https://www.ladypotions.com/episode22" rel="nofollow" target="_blank">Link to sign up for free 29-day meditation challenge</a> <a href="https://www.twitter.com/ladypotions4u" rel="nofollow" target="_blank">@ladypotions4u</a> on Twitter <a href="https://www.instagram.com/ladypotions4u" rel="nofollow" target="_blank">@ladypotions4u</a> on Instagram My Website: <a href="http://www.ladypotions.com/" rel="nofollow" target="_blank">Ladypotions.com</a> Special Thanks to <a href="https://www.christopherlloydclarke.com/" rel="nofollow" target="_blank">Christopher Lloyd Clarke</a> for music Disclaimer * (please include on all iTunes descriptions and show notes) You must not rely on the information in this podcast as an alternative to medical advice from your doctor or other professional healthcare provider. If you have any specific questions about any medical matter you should consult your doctor or other professional healthcare provider. If you think you may be suffering from any medical condition you should seek immediate medical attention. You should never delay seeking medical advice, disregard medical advice, or discontinue medical treatment because of information on this website or in this podcast.

Recurrent Pregnancy Loss with Dr. Zev Williams, M.D. Ph.D., Columbia University