Susan Lindquist, Professor of Biology at the Massachusetts Institute of Technology (MIT), and Member of the Whitehead Institute for Biomedical Research, delivers the 12th Annual Dorfman Memorial Lecture. (December 15, 2009)

Protein Folding Driving Evolutionary Change

Christine Scotti discusses, from the manufacturer's point of view, the use of fluid dynamics in creating endovascular grafts in corroboration with other specialists in the field to maximize device stability. (September 5, 2008)

Computational Fluid Dynamics for Endovascular Graft Design

Charles A. Taylor and Ronald L. Dalman give thanks to all presenters and people involved in the summit and call for future collaboration to better each individual's research results. (September 5, 2008)

Stanford AAA Summit 2008 Closing Remarks

Simona Zannetti, discusses device design from the manufacturer's point of view including the bureaucratic hurdles and testing procedures they face in finding safe and efficient measures to cure AAA disease. (September 5, 2008)

IDE Trial Design for Aortic Aneurysms, Challenges and Opportunities

Christopher K. Zarins discusses the history of the development of endovascular reparation devices, the issue of migration with endograft devices. (September 5, 2008)

Future Design Considerations of Endograft Evolution

Ronald L. Dalman compares the current safety and cost effectiveness of open repair versus endovascular repair of abdominal aortic aneurysms. (September 5, 2008)

Current Status of Surgical Management

David Vorp discusses methods of predicting AAA rupture non-invasively, that is patient specific rather than based solely upon aneurysm diameter. (September 5, 2008)

Predicting AAA Rupture

Jonathan Gillard, discusses morphology and risk, cellular function in drug studies and contrast agents, and the importance of biomechanical processes in studies of AAA using MRI technology. (September 5, 2008)

Imaging Morphological, Functional and Mechanical Interactions in the Carotid & Aorta: the Potential Utility of MRI?

Natzi Sakalihasan, MD, PhD, discusses his clinical studies of 18-FTG uptake by the AAA wall through PET imaging, and hypothesizes that patients with aneurysms of 55 mm diameter or larger could benefit from PET scanning. (September 5, 2008)

Imaging Predictors of AAA Progression

Geoffrey Rubin, MD, discusses the pros and cons of different types of imaging systems available for monitoring AAA progress. (September 5, 2008)

State of the Art in AAA Imaging

Zahi Fayad, PhD, discusses the possibility of using imaging to monitor the effect of angiostatic and anti-inflammatory therapy after administering local drug delivery. (September 5, 2008)

Molecular Imaging of Vascular Disease

B. Timothy Baxter, MD, discusses different studies on chemical treatments that have been shown to effect AAA behavior. (September 4, 2008)

Novel Therapies for AAA

Dianna Milewicz, MD, PhD, discusses the idea that AAA might be partially caused by a rare genetic mutations in addition to environmental conditions that enhance disease progression. (September 5, 2008)

Genetic Determinants of AAA Disease

Ronald L. Dalman, MD discussions the shortcomings of monitoring AAA progression through diameter growth rates, which makes treatment of AAA disease difficult. (September 4, 2008)

Clinical Indicators for Intervention in AAA Disease

Jay Humphrey, PhD, discusses his study of intracranial saccular aneurysms and how his results have mechanical similarities to abdominal aortic aneurisms in areas like blood flow and wall stress. (September 4, 2008)

Vascular Mechanobiology: Modeling the Growth of AAA

Charles A. Taylor, PhD, discusses his research at Stanford university on blood flow distribution and wall shear stress in the abdominal aorta to learn how the growth of AAA can be effected through exercise and rest conditions. (September 4, 2008)

Hemodynamic Predictors of Disease Progression

Paul Norman, DS, FRACS, discusses several different types of biomarkers, both chemical and genetic, and the need for greater instances of replication and screening to find more conclusive evidence for therapeutic methods. (September 4, 2008)

Biomarkers/Biologic Predictors of Disease Progression

Roberty Peattie, PhD, discusses his research of flow fields in physically replicated models of the human aorta to discover the velocity of flow which causes wall shear stresses. (September 4, 2008)

Experimental Measurements of AAA Hemodynamics

Neal Weintraub, MD, discusses his research on oxidative stress locally increased in Abdominal Aortic Aneurysm Disease and the possibility that Taurine might be a safe mode of therapy for humans. (September 4, 2008)

The Role of Oxidative Stress and AAA Pathobiology

Gerhard Holzapfel, PhD, discusses the nonlinear behavior of an aorta under stress testing. (September 4, 2008)

Biomechanics of the Aorta

Abdominal Aortic Aneurysm Summit

Robert Thompson, MD discusses the growth and inhibition of growth in abdominal aortic aneurysms through the degradation of elastin in his mouse model. (September 4, 2008)

AAA Insights from the Elastase-induced Rodent Model

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