Cover image of Please Explain (The Leonard Lopate Show)

Please Explain (The Leonard Lopate Show)

In Please Explain, we set aside time every Friday afternoon to get to the bottom of one complex issue. Ever wonder how New York City's water system works? Or how the US became so polarized politically... Read more

Ranked #1

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Why Are Life-Saving Drugs So Expensive?

Why Are Life-Saving Drugs So Expensive?

When Turing Pharmaceuticals raised the price of a life-saving drug from $13.50 to $750 a pill, it brought the issue of d... Read more

16 Oct 2015

35mins

Ranked #2

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How to Make Arguments... And Win!

How to Make Arguments... And Win!

Sometimes it's impossible to avoid an argument. That's why on today's Please Explain, we're learning how to make a convi... Read more

15 Jul 2016

26mins

Ranked #3

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Sweet Dreams (and Nightmares) Are Made of This

Sweet Dreams (and Nightmares) Are Made of This

Dreams are a natural part of life, and throughout human history, people have tried to interpret their dreams. But dreami... Read more

23 Sep 2016

32mins

Ranked #4

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Understanding CRISPR, the Sci-Fi-Esque Gene Editing Tool

Understanding CRISPR, the Sci-Fi-Esque Gene Editing Tool

Science journalist Jennifer Kahn joins us for this week’s Please Explain, which is all about CRISPR, an incredible tool ... Read more

24 Feb 2017

33mins

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Ranked #5

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The Science Of Success

The Science Of Success

Eric Barker is the author of Barking Up the Wrong Tree: The Surprising Science Behind Why Everything You Know About Succ... Read more

9 Jun 2017

27mins

Ranked #6

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Why Fat Is So Misunderstood

Why Fat Is So Misunderstood

Our latest Please Explain is all about fat with Dr. Sylvia Tara, author of The Secret Life of Fat: The Science Behind th... Read more

6 Jan 2017

33mins

Ranked #7

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The Unbalanced Power of Expert Witnesses

The Unbalanced Power of Expert Witnesses

In our latest Please Explain, we examine expert witnesses to find out their role in courts, their influence in trials, a... Read more

20 Nov 2015

31mins

Ranked #8

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The Secret Life of Ballerinas

The Secret Life of Ballerinas

The best ballerinas make it look effortless, gracefully dancing and leaping across the stage in beautiful costumes. But ... Read more

16 Sep 2016

28mins

Ranked #9

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How To Succeed Even If You're An Introvert

How To Succeed Even If You're An Introvert

For our latest Please Explain, we explore what it means to be an introvert and what pressures they face when advancing t... Read more

20 Oct 2017

36mins

Ranked #10

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How Addiction Works

How Addiction Works

For this week's Please Explain, we explore how science is giving us a better understanding of how addiction works, and w... Read more

13 Oct 2017

31mins

Ranked #11

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Unwrapping the History of Paper

Unwrapping the History of Paper

For the past 2000 years, paper has been the essential object that fuels education, art, commerce, dissemination of ideas... Read more

10 Jun 2016

32mins

Ranked #12

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The History of Restaurants Revealed

The History of Restaurants Revealed

Centuries before the restaurant became a dining destination, a "restaurant" was actually a medicinal broth that containe... Read more

14 Oct 2016

27mins

Ranked #13

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All The Light We Cannot See

All The Light We Cannot See

Our latest Please Explain is about invisible currents that exist all around us with Bob Berman, author of the book Zappe... Read more

11 Aug 2017

17mins

Ranked #14

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Understanding Psychosomatic Illness

Understanding Psychosomatic Illness

For this week’s Please Explain, we discuss psychosomatic illnesses and the mind-body connection with Dr. Suzanne O’Sulli... Read more

7 Apr 2017

30mins

Ranked #15

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Listening to Body Language

Listening to Body Language

When is a shrug just a shrug? What are you really saying when you fold your arms across your chest? Whether we know it o... Read more

27 Jan 2017

24mins

Ranked #16

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How To Go Vegan

How To Go Vegan

Our first Food Fridays Please Explain kicks off with vegan cooking! Ronen Seri and Pamela Elizabeth are the co-founders ... Read more

27 Oct 2017

30mins

Ranked #17

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How To Cut The Clutter And Get Organized

How To Cut The Clutter And Get Organized

If your desk is a total mess, today’s Please Explain is meant for YOU! We tackle the crucial, yet all-so-difficult task,... Read more

14 Jul 2017

31mins

Ranked #18

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What's Keeping You Up at Night?

What's Keeping You Up at Night?

Why can’t we sleep? The CDC estimates that 50 to 70 million U.S. adults have a sleep or wakefulness disorder, caused by ... Read more

9 Dec 2016

31mins

Ranked #19

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The Science of Cheese

The Science of Cheese

Ever wonder why Swiss cheese has holes? Why are so many types of cheese yellow in color? Or, what kinds of milk are best... Read more

4 Nov 2016

26mins

Ranked #20

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Why We Love To Run

Why We Love To Run

For our next Please Explain, Vybarr Cregan-Reid jogs us through the basics of running. Cregan-Reid, who authored the boo... Read more

18 Aug 2017

34mins

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