Episode 62 Show Notes July 2023  Comparison of endoscopic sleeve gastroplasty versus surgical sleeve gastrectomy: a database analysis. – GIE Incidence and natural history of gastric high grade dysplasia in patients with FAP. – GIE Association of Life Expectancy with surveillance colonoscopy findings and follow up recommendations in Older adults – Jama IM Physician decision-making about surveillance in older adults with prior adenomas: results from a national study. – Am J Gastro Hpylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT) – RCT – Lancet 2022 Effectiveness and Safety of Colonic and Capsule Fecal Microbiota Transplantation for Recurrent Clostridiodes difficile Infection – CGH  Tweet

Episode 62 Show Notes July 2023 <ol> <li>Comparison of endoscopic sleeve gastroplasty versus surgical sleeve gastrectomy: a database analysis. – GIE</li> <li>Incidence and natural history of gastric high grade dysplasia in patients with FAP. – GIE</li> <li>Association of Life Expectancy with surveillance colonoscopy findings and follow up recommendations in Older adults – Jama IM</li> <li>Physician decision-making about surveillance in older adults with prior adenomas: results from a national study. – Am J Gastro</li> <li>Hpylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT) – RCT – Lancet 2022</li> <li>Effectiveness and Safety of Colonic and Capsule Fecal Microbiota Transplantation for Recurrent Clostridiodes difficile Infection – CGH</li> </ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2023%2F07%2F15%2Fgi-pearls-episode-62%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls Gastroenterology Podcast Episode 62

Episode 61 Show Notes June 2023  Efficacy of a Second PPI Course After Steroid-induced remission in EOE refractory to initial PPI therapy. – ACG AGA Clinical Practice Update on Management of Subepithelial Lesions encountered during routine Endoscopy: Expert Review – CGH Prune juice Containing Sorbitol, Pectin and Polyphenol Ameliorates subjective complaints and Hard Feces while Normalizing Stool in Chronic constipation: A randomized placebo-controlleD Trial. – Am J Gastro Adenoma Detection Rate and Risk for Interval Post colonoscopy Colorectal Cancer in Fecal Immunochemical Test–Based Screening – Annals of IM Latiglutenase Protects the mucosa and attenuates symptom severity in patients with celiac disease exposed to a gluten challenge – Gastro Evaluation of real-time computer-aided polyp detection system during screening colonoscopy: AI-DETECT study – Endoscopy  Tweet

Episode 61 Show Notes June 2023 <ol> <li><a href="https://journals.lww.com/ajg/Abstract/2022/10000/Efficacy_of_a_Second_PPI_Course_After.29.aspx" rel="nofollow" target="_blank">Efficacy of a Second PPI Course After Steroid-induced remission in EOE refractory to initial PPI therapy.</a> – ACG</li> <li><a href="https://www.cghjournal.org/article/S1542-3565(22)00640-1/fulltext" rel="nofollow" target="_blank">AGA Clinical Practice Update on Management of Subepithelial Lesions encountered during routine Endoscopy: Expert Review</a> – CGH</li> <li><a href="https://journals.lww.com/ajg/Fulltext/2022/10000/Prune_Juice_Containing_Sorbitol,_Pectin,_and.32.aspx" rel="nofollow" target="_blank">Prune juice Containing Sorbitol, Pectin and Polyphenol Ameliorates subjective complaints and Hard Feces while Normalizing Stool in Chronic constipation: A randomized placebo-controlleD Trial. </a>– Am J Gastro</li> <li><a href="https://www.acpjournals.org/doi/10.7326/M22-0301" rel="nofollow" target="_blank">Adenoma Detection Rate and Risk for Interval Post colonoscopy Colorectal Cancer in Fecal Immunochemical Test–Based Screening</a> – Annals of IM</li> <li><a href="https://www.gastrojournal.org/article/S0016-5085(22)00901-5/fulltext" rel="nofollow" target="_blank">Latiglutenase Protects the mucosa and attenuates symptom severity in patients with celiac disease exposed to a gluten challenge</a> – Gastro</li> <li><a href="https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1966-0661" rel="nofollow" target="_blank">Evaluation of real-time computer-aided polyp detection system during screening colonoscopy: AI-DETECT study</a> – Endoscopy</li> </ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2023%2F06%2F05%2Fgi-pearls-episode-61%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls Gastroenterology Podcast Episode 61

Show Notes for GI Pearls Episode 60 What is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Updated Systematic Review and Meta-analysis – CGHQuality of upper GI endoscopy: a prospective cohort study on impact of endoscopist education – GIEAssociation between endoscopist specialty and colonoscopy quality: a systematic Review and meta-analysis. – CGHNet Remission Rates with Biologic Treatment in Crohn’s  Disease: A Reappraisal of the Clinical Trial Data  – CGH Tweet

Show Notes for GI Pearls Episode 60 <ol><li>What is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Updated Systematic Review and Meta-analysis – CGH</li><li>Quality of upper GI endoscopy: a prospective cohort study on impact of endoscopist education – GIE</li><li>Association between endoscopist specialty and colonoscopy quality: a systematic Review and meta-analysis. – CGH</li><li>Net Remission Rates with Biologic Treatment in Crohn’s  Disease: A Reappraisal of the Clinical Trial Data  – CGH</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2022%2F10%2F22%2Fgi-pearls-episode-60%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls Gastroenterology Podcast Episode 60

Show notes for Episode 59 GI Pearls Podcast Cannabidiol for Functional Dyspepsia With Normal Gastric Emptying: a RCT. – Am J GastroRandomized Controlled Trial Investigating Cold Snare and Forceps Polypectomy among small POLYPs in Rates of Complete Resection: The TINYPOLYP Trial – Am J GastroVonoprazan triple and dual therapy for Hpylori infection in the United States and Europe: RCT – GastroAggressive or Moderate Fluid Resuscitation in Acute Pancreatitis – NEJM Tweet

Show notes for Episode 59 GI Pearls Podcast <ol><li>Cannabidiol for Functional Dyspepsia With Normal Gastric Emptying: a RCT. – Am J Gastro</li><li>Randomized Controlled Trial Investigating Cold Snare and Forceps Polypectomy among small POLYPs in Rates of Complete Resection: The TINYPOLYP Trial – Am J Gastro</li><li>Vonoprazan triple and dual therapy for Hpylori infection in the United States and Europe: RCT – Gastro</li><li>Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis – NEJM</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2022%2F09%2F25%2Fgi-pearls-episode-59-short%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls Gastroenterology Podcast Episode 59 Short

Episode 58 Show notes Cold versus hot snare resection with or without submucosal injection of 6-15mm colorectal polyps: RCT. – GIEProspective cohort study to investigate the safety of preoperative tumor necrosis factor inhibitor exposure in patients with inflammatory bowel disease undergoing intra-abdominal surgery.  – GastroenterologyClip Closure does not reduce risk of bleeding after resection of large serrated polyps: Results from a randomized trial. – CGH Tweet

Episode 58 Show notes <ol><li>Cold versus hot snare resection with or without submucosal injection of 6-15mm colorectal polyps: RCT. – GIE</li><li>Prospective cohort study to investigate the safety of preoperative tumor necrosis factor inhibitor exposure in patients with inflammatory bowel disease undergoing intra-abdominal surgery.  – Gastroenterology</li><li>Clip Closure does not reduce risk of bleeding after resection of large serrated polyps: Results from a randomized trial. – CGH</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2022%2F09%2F11%2Fgi-pearls-episode-58-short%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls Gastroenterology Podcast Episode 58 Short

Articles discussed Clinically significant serrated polyp detection rates and risk for postcolonoscopy colorectal cancer: data from the New Hampshire Colonoscopy Registry – GIEPolyps seen but not removed during index colonoscopy: an underestimated inefficiency in endoscopy practice. – GIEFecal Microbiota transplant is a good treatment for recurrent C.difficile and there were several randomized clinical trials showing it’s efficacy, mostly small, but with really good results. Please send me comments, suggestions to info@gipearls dot com.  If you could also leave a good review on iTunes or your podcatcher of choice – this would go a long way.  Tweet

Articles discussed <ol><li>Clinically significant serrated polyp detection rates and risk for postcolonoscopy colorectal cancer: data from the New Hampshire Colonoscopy Registry – GIE</li><li>Polyps seen but not removed during index colonoscopy: an underestimated inefficiency in endoscopy practice. – GIE</li><li>Fecal Microbiota transplant is a good treatment for recurrent C.difficile and there were several randomized clinical trials showing it’s efficacy, mostly small, but with really good results.</li></ol> Please send me comments, suggestions to info@gipearls dot com. If you could also leave a good review on iTunes or your podcatcher of choice – this would go a long way. <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2022%2F08%2F28%2Fgi-pearls-episode-57-short%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls Episode 57 Short

Episode 56 – New Short Format Articles discussed: Once-only colonoscopy or two rounds of faecal immunochemical testing 2 years apart for colorectal cancer screening: preliminary report of a randomised controlled trial – Lancet Gastro HepVedolizumab is associated with a lower risk of Serious Infectious than Anti-Tumor Factors Agents in Older Adults – CGH please feel free to add your comments on https://gipearls.com/category/podcast/ – just select the episode and leave comments on the bottom of the page. Otherwise see you on twitter @GI_Pearls Tweet

Episode 56 – New Short Format Articles discussed: <ol><li>Once-only colonoscopy or two rounds of faecal immunochemical testing 2 years apart for colorectal cancer screening: preliminary report of a randomised controlled trial – Lancet Gastro Hep</li><li>Vedolizumab is associated with a lower risk of Serious Infectious than Anti-Tumor Factors Agents in Older Adults – CGH</li></ol> please feel free to add your comments on <a href="https://gipearls.com/category/podcast/" rel="nofollow" target="_blank">https://gipearls.com/category/podcast/</a> – just select the episode and leave comments on the bottom of the page. Otherwise see you on twitter @GI_Pearls <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2022%2F08%2F13%2Fepisode-56-short%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls Gastroenterology Podcast Episode 56 - Short

Show notes for Episode 55 – June 2022 Pooled Rates of Adenoma Detection by Colonoscopy in Asymptomatic Average Risk Individuals with Positive Fecal Immunochemical Test: A Systematic Review and Meta-Analysis – GIELong-Term Follow-up of the Italian Flexible Sigmoidoscopy Screening Trial – Annals of IMRecurrence of Colorectal neoplastic polyps after incomplete resection  – annals of internal MedicineA randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being – Scientific ReportsAssociations between autoimmune conditions and gastric cancer risk among elderly adults in the united states – Am J GastroPatient satisfaction of Propofol versus Midazolam and Fentanyl Sedation during colonoscopy in IBD – CGHComorbidities Drive the Majority of Overall Mortality in Low-risk Mucinous Pancreatic Cysts Under Surveillance – CGHImplications of stable or increasing adenoma detection rate on the need for continuous measurement. – GIEMargin marking before colorectal endoscopic mucosal resection and its impact on neoplasia recurrence. – GIEPercutaneous Tibial nerve Stimulation vs Sham Stimulation For Fecal incontinence in Women: Neuromodulation for accidental bowel leakage Randomized Clinical Trial – ACGACG-CAG Clinical Practice Guideline :Management of Anticoagulants and Antiplatelets during acute GI bleed – ACG Guidelines Tweet

Show notes for Episode 55 – June 2022 <ol><li>Pooled Rates of Adenoma Detection by Colonoscopy in Asymptomatic Average Risk Individuals with Positive Fecal Immunochemical Test: A Systematic Review and Meta-Analysis – GIE</li><li>Long-Term Follow-up of the Italian Flexible Sigmoidoscopy Screening Trial – Annals of IM</li><li>Recurrence of Colorectal neoplastic polyps after incomplete resection  – annals of internal Medicine</li><li>A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being – Scientific Reports</li><li>Associations between autoimmune conditions and gastric cancer risk among elderly adults in the united states – Am J Gastro</li><li>Patient satisfaction of Propofol versus Midazolam and Fentanyl Sedation during colonoscopy in IBD – CGH</li><li>Comorbidities Drive the Majority of Overall Mortality in Low-risk Mucinous Pancreatic Cysts Under Surveillance – CGH</li><li>Implications of stable or increasing adenoma detection rate on the need for continuous measurement. – GIE</li><li>Margin marking before colorectal endoscopic mucosal resection and its impact on neoplasia recurrence. – GIE</li><li>Percutaneous Tibial nerve Stimulation vs Sham Stimulation For Fecal incontinence in Women: Neuromodulation for accidental bowel leakage Randomized Clinical Trial – ACG</li><li>ACG-CAG Clinical Practice Guideline :Management of Anticoagulants and Antiplatelets during acute GI bleed – ACG Guidelines</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2022%2F06%2F05%2Fepisode-55-june-2022-gastroenterology-literature-review%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

Episode 55 – June 2022 – Gastroenterology Literature Review

Show notes Episode 54 – May 2022 A Randomized Controlled Trial of Cold Snare Polypectomy Technique: Technique Matters More Than Snare Wire Diameter – Am J GastroOutcomes for upper gastrointestinal bleeding during the first wave of the COVID-19 pandemic in the Toronto area – J Gastro and Hep Endoscopic Surveillance of Barrett’s Esophagus – using old principles and new technology to improve Care. – Am J GastroThree signs of pneumoperitoneum on a Supine Radio-graph – CGHComparison of a Hemostatic Powder and Standard Treatment in the Control of Active Bleeding From Upper Nonvariceal Lesions – Annals of Int MedicineAssociations Between Sleep Position and Nocturnal Gastroesophageal Reflux: A Study Using Concurrent Monitoring of Sleep Position and Esophageal pH and Impedance – ACGArtificial intelligence for the assessment of bowel preparation – GIEDiagnostic Yeild of colonoscopy in Patients with Symptoms Compatible with Rome IV Functional Bowel Disorders . – CGH Tweet

Show notes Episode 54 – May 2022 <ol><li>A Randomized Controlled Trial of Cold Snare Polypectomy Technique: Technique Matters More Than Snare Wire Diameter – Am J Gastro</li><li>Outcomes for upper gastrointestinal bleeding during the first wave of the COVID-19 pandemic in the Toronto area – J Gastro and Hep </li><li>Endoscopic Surveillance of Barrett’s Esophagus – using old principles and new technology to improve Care. – Am J Gastro</li><li>Three signs of pneumoperitoneum on a Supine Radio-graph – CGH</li><li>Comparison of a Hemostatic Powder and Standard Treatment in the Control of Active Bleeding From Upper Nonvariceal Lesions – Annals of Int Medicine</li><li>Associations Between Sleep Position and Nocturnal Gastroesophageal Reflux: A Study Using Concurrent Monitoring of Sleep Position and Esophageal pH and Impedance – ACG</li><li>Artificial intelligence for the assessment of bowel preparation – GIE</li><li>Diagnostic Yeild of colonoscopy in Patients with Symptoms Compatible with Rome IV Functional Bowel Disorders . – CGH</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2022%2F05%2F01%2Fepisode-54-may-2022-gastroenterology-literature-review%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

Episode 54 – May 2022 – Gastroenterology Literature Review

Show Notes for Episode 53 Lyophilised oral fecal microbiota transplantation for ulcerative colitis (LOTUS): a randomised, double-blind, placebo-controlled trial. – Lancet GastroEffect of prophylactic endoscopic clip placement on clinically significant post-endoscopic mucosal resection bleeding in the right colon: a single centre, randomized controlled trial – Lancet GastroFeasibility and diagnostic yield of small-bowel capsule endoscopy in patients with surgically altered gastric anatomy: the SAGA study – GIEUtility of Serum Biomarker Indices for staging of Hepatic Fibrosis before and after venesection in patients with Hemochromatosis caused by Variants in HFE – CGHBarrett’s esophagus with low-grade dysplasia: high rate of upstaging at Barrett’s esophagus referral units suggests progression rates may be overestimated.  – GIEACG Clinical Guideline for the diagnosis and management of GERD – Am J GastroDiagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – ACP – Annals of IM Tweet

Show Notes for Episode 53 <ol><li>Lyophilised oral fecal microbiota transplantation for ulcerative colitis (LOTUS): a randomised, double-blind, placebo-controlled trial. – Lancet Gastro</li><li>Effect of prophylactic endoscopic clip placement on clinically significant post-endoscopic mucosal resection bleeding in the right colon: a single centre, randomized controlled trial – Lancet Gastro</li><li>Feasibility and diagnostic yield of small-bowel capsule endoscopy in patients with surgically altered gastric anatomy: the SAGA study – GIE</li><li>Utility of Serum Biomarker Indices for staging of Hepatic Fibrosis before and after venesection in patients with Hemochromatosis caused by Variants in HFE – CGH</li><li>Barrett’s esophagus with low-grade dysplasia: high rate of upstaging at Barrett’s esophagus referral units suggests progression rates may be overestimated.  – GIE</li><li>ACG Clinical Guideline for the diagnosis and management of GERD – Am J Gastro</li><li>Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – ACP – Annals of IM</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2022%2F02%2F22%2Fepisode-53-february-2022-gastroenterology-literature-review%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls Gastroenterology Podcast Episode 53 - February 2022

Highly recommended. Clear, humble and straight to the point.

Excellent show

Excellent clinical coverage, great review of recent literature.

Great podcast!

GI Pearls Podcast

Show notes for Episodes 40 – May 2020 Choosing a prokinetic for your patient beyond metoclopramide – AmJ GastroUltraprocessed Food Consumption and Risk of T2DM among participants of the NutriNet-Sante Prospective Cohort – JAMA Int MedDiagnosis and Treatment of Clostridioides (Clostridium) difficile  Infection  in Adults in 2020 – JAMAClinical importance of cold polypectomy during the insertion phase in the left side of the colon and rectum: multicenter randomized controlled trial (PRESECT study). –  GIETiming of endoscopy for Acute Upper Gastrointestinal Bleeding – NEJMTrends in US Burden of C.difficile infection – NEJMMechanism, Evaluation and Management of Chronic Constipation – GastroenterologyUndisclosed payments by pharmaceutical and medical device manufacturers to authors of endoscopy guidelines in the United States – GIEManaging conflicts of interest in clinical practice guidelines – GIEHepatopulmonary Syndrome – NEJMReversal of Digital Clubbing After Lung Transplantation in Cystic Fibrosis Patients:  A Clue to the Pathogenesis of Clubbing – Pediatr Pulmonol. Infectious Proctitis – NEJM  Intestinal Lipomatosis – NEJM EUS-guided gastroenteric anastomosis as a bridge to  definitive treatment in benign gastric outlet obstruction – GIEUptake of Colorectal Cancer Screening by Physicians  Is  Associated With Greater Uptake by Their Patients – GastroImmunosuppression in Autoimmune Hepatitis: Is There an End Game? – Am J Gastro Tweet

Show notes for Episodes 40 – May 2020 <ol><li>Choosing a prokinetic for your patient beyond metoclopramide – AmJ Gastro</li><li>Ultraprocessed Food Consumption and Risk of T2DM among participants of the NutriNet-Sante Prospective Cohort – JAMA Int Med</li><li>Diagnosis and Treatment of Clostridioides (Clostridium) difficile  Infection  in Adults in 2020 – JAMA</li><li>Clinical importance of cold polypectomy during the insertion phase in the left side of the colon and rectum: multicenter randomized controlled trial (PRESECT study). –  GIE</li><li>Timing of endoscopy for Acute Upper Gastrointestinal Bleeding – NEJM</li><li>Trends in US Burden of C.difficile infection – NEJM</li><li>Mechanism, Evaluation and Management of Chronic Constipation – Gastroenterology</li><li>Undisclosed payments by pharmaceutical and medical device manufacturers to authors of endoscopy guidelines in the United States – GIE</li><li>Managing conflicts of interest in clinical practice guidelines – GIE</li><li>Hepatopulmonary Syndrome – NEJM</li><li>Reversal of Digital Clubbing After Lung Transplantation in Cystic Fibrosis Patients:  A Clue to the Pathogenesis of Clubbing – Pediatr Pulmonol.</li><li> Infectious Proctitis – NEJM </li><li> Intestinal Lipomatosis – NEJM</li><li> EUS-guided gastroenteric anastomosis as a bridge to  definitive treatment in benign gastric outlet obstruction – GIE</li><li>Uptake of Colorectal Cancer Screening by Physicians  Is  Associated With Greater Uptake by Their Patients – Gastro</li><li>Immunosuppression in Autoimmune Hepatitis: Is There an End Game? – Am J Gastro</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2020%2F05%2F16%2Fgi-pearls-may-2020-episode-40-gastroenterology-literature-review%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls May - 2020

Show notes for Episodes 39 – February-March 2020 Prevalence of colorectal cancer and advanced adenoma in patients with acute diverticulitis – GIEPancreatic tuberculosis: A systematic review of symptoms, diagnosis and treatment – UEGJournalRecommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – GastroRisk of progression of Barrett’s esophagus indefinite for dysplasia: Meta-analysis – GIEAGA Clinical Pratice Update – Management of Pancreatic Necrosis – GastroEstablishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents – CellNeutropenic Enterocolitis: Clinical  Features and Outcomes – Dis Colon Rectum. Long-term Risk of Malignancy in Branch-Duct  Intraductal Papillary Mucinous Neoplasms – GastroIncreased incidence and Mortality of Gastric Cancer in Immigrant Population from High to Low Regions of Incidence: Systematic Review – CGHAGA: Clinical Practice Guidelines on management of Gastric Intestinal Metaplasia – Gastro  Tweet

Show notes for Episodes 39 – February-March 2020 <ol><li>Prevalence of colorectal cancer and advanced adenoma in patients with acute diverticulitis – GIE</li><li>Pancreatic tuberculosis: A systematic review of symptoms, diagnosis and treatment – UEGJournal</li><li>Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastro</li><li>Risk of progression of Barrett’s esophagus indefinite for dysplasia: Meta-analysis – GIE</li><li>AGA Clinical Pratice Update – Management of Pancreatic Necrosis – Gastro</li><li>Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents – Cell</li><li>Neutropenic Enterocolitis: Clinical  Features and Outcomes – Dis Colon Rectum. </li><li>Long-term Risk of Malignancy in Branch-Duct  Intraductal Papillary Mucinous Neoplasms – Gastro</li><li>Increased incidence and Mortality of Gastric Cancer in Immigrant Population from High to Low Regions of Incidence: Systematic Review – CGH</li><li>AGA: Clinical Practice Guidelines on management of Gastric Intestinal Metaplasia – Gastro</li></ol> <a href="https://twitter.com/intent/tweet?text=GI%20Pearls%20-%20Episode%2039%20-%20March%2FApril%202020%20Gastroenterology%20and%20Hepatology%20Literature%20Review&amp;url=https%3A%2F%2Fgipearls.com%2F2020%2F04%2F01%2Fgi-pearls-march-april-2020-episode-39-gastroenterology-literature-review%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls March/April- 2020

   Show Notes for November 2019 – Episode 36 Detection of Various Microplastics in Human stool – Annals of int MedHerpes Zoster in Tofacitinib: Risk is Further Increased with Glucocorticoids but not Methotrexate – Arthritis Care ResFatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae  – CellIncidence of and Risk Factors for  Hepatic Encephalopathy in a Population-Based Cohort of Americans – Hepatology CommunicationsFFP transfusion in patients with cirrhosis and coagulopathy: effect on conventional coagulation tests and thrombomodulin-modified thrombin generation  – J Hepatol.Effect of Chromoendoscopy in the proximal colon on Colorectal neoplasia detection in Lynch syndrome: A multicenter randomized controlled trial. – GIETerminology, Molecular featuers, Epidemiology, and Management of Serrated Colon neoplaisa.Providing data for serrated polyp detection rate benchmarks – GIE Management of Nonvariceal Upper GI bleeding: Guideline recommendations from the International Consensus Group – Ann of Int MedEfficacy of Prophylactic Hemoclips in prevention of delayed post-polypectomy Bleeding in patients with large colonic polyps – GastroClip Closure Prevents Bleeding After Endoscopic resection of large colon polyps in a randomized trial – Gastro  Tweet

Show Notes for November 2019 – Episode 36 <ol><li>Detection of Various Microplastics in Human stool – Annals of int Med</li><li>Herpes Zoster in Tofacitinib: Risk is Further Increased with Glucocorticoids but not Methotrexate – Arthritis Care Res</li><li>Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae  – Cell</li><li>Incidence of and Risk Factors for  Hepatic Encephalopathy in a Population-Based Cohort of Americans – Hepatology Communications</li><li>FFP transfusion in patients with cirrhosis and coagulopathy: effect on conventional coagulation tests and thrombomodulin-modified thrombin generation  – J Hepatol.</li><li>Effect of Chromoendoscopy in the proximal colon on Colorectal neoplasia detection in Lynch syndrome: A multicenter randomized controlled trial. – GIE</li><li>Terminology, Molecular featuers, Epidemiology, and Management of Serrated Colon neoplaisa.</li><li><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438272/" rel="nofollow" target="_blank">Providing data for serrated polyp detection rate benchmarks</a> – GIE </li><li><a href="https://annals.org/aim/fullarticle/2753604/management-nonvariceal-upper-gastrointestinal-bleeding-guideline-recommendations-from-international-consensus" rel="nofollow" target="_blank">Management of Nonvariceal Upper GI bleeding: Guideline recommendations from the International Consensus Group</a> – Ann of Int Med</li><li>Efficacy of Prophylactic Hemoclips in prevention of delayed post-polypectomy Bleeding in patients with large colonic polyps – Gastro</li><li>Clip Closure Prevents Bleeding After Endoscopic resection of large colon polyps in a randomized trial – Gastro</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2019%2F11%2F24%2Fgi-pearls-october-2019-episode-35-gastroenterology-literature-review-2%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls November 2019

 Show Notes for Oct 2019 – Episode 35 Appropriate therapeutic drug monitoring of Biologic agents for Patients with IBD – CGHThe View from Europe – TDM  – CGH Cold snare vs Heparin bridging and hot snare polypectomy in patients on anticoagulants with subcentimeter polyps. – Annals of int Med.High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength – JAMASafety of Endoscopy in Heritable Connective Tissue Disorders – Am J GastroASGE guideline on screening and surveillance of Barrett’s esophagus – ASGEPrucalporide in Gastroparesis: A Randomized Placebo-controlled Crossover Study. – Am J GastroOver-Utilization of Repeat Upper Endoscopy in patients with non-dysplastic Barrett’s esophagus – Am J GastroControlling fecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomized clinical trial. – Lancet Gastro &amp;Hep Toshihiro Sugiyama  Understanding the Current Evidence on Proton Pump Inhibitor Use and Bone Health – GastroUrsodeoxycholic acid versus placebo in women  with intrahepatic cholestasis of pregnancy (PITCHES):a randomised controlled trial – Lancet’Effect of Bismuth Subsalicylate vs Placebo on Use of Antibiotics Among Adult Outpatients With Diarrhea in Pakistan: A Randomized Clinical Trial. –  JAMA Netw OpenAssociation between soft drink consumption and mortality in 10 european countries. – JAMAValidation of Diagnostic and Performance Characteristics of the Wireless Motility Capsule in Patients with Suspected Gastroparesis – CGHVedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis – NEJMUstekinumab for Ulcerative Colitis – NEJM  Tweet

Show Notes for Oct 2019 – Episode 35 <ol><li><a href="https://www.cghjournal.org/article/S1542-3565%2819%2930301-5/fulltext" rel="nofollow" target="_blank">Appropriate therapeutic drug monitoring of Biologic agents for Patients with IBD</a> – CGH</li><li><a href="https://www.cghjournal.org/article/S1542-3565%2819%2930728-1/fulltext#sec1" rel="nofollow" target="_blank">The View from Europe – TDM </a> – CGH </li><li>Cold snare vs Heparin bridging and hot snare polypectomy in patients on anticoagulants with subcentimeter polyps. – Annals of int Med.</li><li>High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength – JAMA</li><li>Safety of Endoscopy in Heritable Connective Tissue Disorders – Am J Gastro</li><li>ASGE guideline on screening and surveillance of Barrett’s esophagus – ASGE</li><li>Prucalporide in Gastroparesis: A Randomized Placebo-controlled Crossover Study. – Am J Gastro</li><li>Over-Utilization of Repeat Upper Endoscopy in patients with non-dysplastic Barrett’s esophagus – Am J Gastro</li><li>Controlling fecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomized clinical trial. – Lancet Gastro &amp;Hep</li><li> Toshihiro Sugiyama  <a href="https://www.gastrojournal.org/article/S0016-5085%2819%2940886-X/pdf" rel="nofollow" target="_blank">Understanding the Current Evidence on Proton Pump Inhibitor Use and Bone Health</a> – Gastro</li><li>Ursodeoxycholic acid versus placebo in women  with intrahepatic cholestasis of pregnancy (PITCHES):a randomised controlled trial – Lancet’</li><li>Effect of Bismuth Subsalicylate vs Placebo on Use of Antibiotics Among Adult Outpatients With Diarrhea in Pakistan: A Randomized Clinical Trial. –  JAMA Netw Open</li><li>Association between soft drink consumption and mortality in 10 european countries. – JAMA</li><li>Validation of Diagnostic and Performance Characteristics of the Wireless Motility Capsule in Patients with Suspected Gastroparesis – CGH</li><li>Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis – NEJM</li><li>Ustekinumab for Ulcerative Colitis – NEJM</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2019%2F10%2F08%2Fgi-pearls-october-2019-episode-35-gastroenterology-literature-review%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls October 2019

 Show Notes for December 2019 – Episode 37  Assessment of Publication Trends of Systematic Reviews and RCTs – JAMA Int Med.Association between Hpylori exposure and decreased odds of EOE – CGHEffect of anti-Hpylori therapy on incidence of autoimmune diseases,  – CGHAGA Practice Update on Surveillance for cancer in patients with PSC – Gastro.Screening for colorectal cancer in asymptomatic average-risk adults: ACP guideline – Annals of Int MedHigh intensity versus low intensity surveillance for patients with colorectal adenomas – Annals of Int medInfliximab-Tumor Necrosis Factor complexes Elicif formation of Anti-Drug Antibodies – GastroOutcomes of Patients with IBD switched from maintenance therapy with a biosimilar to Remicade – CGHLactose drives Enterococcus expansion to promote graft-versus-host disease – Science The association between dietary fiber deficiency and high-income lifestyle-associated diseses: Burkitt’s hypothesis revisited. Compared abilities of endoscopic techniques to increase colon adenoma detection rates – CGHAdvanced imaging for detection and differentiation of colorectal neoplasia:ESGE Guidelines – Endoscopy Tweet

Show Notes for December 2019 – Episode 37 <ol><li>Assessment of Publication Trends of Systematic Reviews and RCTs – JAMA Int Med.</li><li>Association between Hpylori exposure and decreased odds of EOE – CGH</li><li>Effect of anti-Hpylori therapy on incidence of autoimmune diseases,  – CGH</li><li>AGA Practice Update on Surveillance for cancer in patients with PSC – Gastro.</li><li>Screening for colorectal cancer in asymptomatic average-risk adults: ACP guideline – Annals of Int Med</li><li>High intensity versus low intensity surveillance for patients with colorectal adenomas – Annals of Int med</li><li>Infliximab-Tumor Necrosis Factor complexes Elicif formation of Anti-Drug Antibodies – Gastro</li><li>Outcomes of Patients with IBD switched from maintenance therapy with a biosimilar to Remicade – CGH</li><li>Lactose drives Enterococcus expansion to promote graft-versus-host disease – Science </li><li>The association between dietary fiber deficiency and high-income lifestyle-associated diseses: Burkitt’s hypothesis revisited. </li><li>Compared abilities of endoscopic techniques to increase colon adenoma detection rates – CGH</li><li>Advanced imaging for detection and differentiation of colorectal neoplasia:ESGE Guidelines – Endoscopy</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2019%2F12%2F27%2Fgi-pearls-december-2019-episode-37-gastroenterology-literature-review%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls December 2019

   Show notes for Episodes 38 – January 2020 ASGE review of adverse events in colonoscopy – GIE Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia – NEJMRelationship Between Recreational Marijuana  Use and Bowel Function in a Nationwide Cohort Study – Am J gastroCirculating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and  screening for colorectal cancer – Science TMLactulose Breath Testing as a Predictor of  Response to Rifaximin in Patients With Irritable bowel  Syndrome With Diarrhea – AmJ GastroPostinfectious IBS after Campylobacter infection – Am J GastroOral Curcumin no more effective than placebo in preventing recurrence of Crohn’s disease after surgery in RTC – CGH Hpylori – when treat when not to treat – Am J GastroLong-Duration Oral Vancomycin to treat Cdiff in patients iwth IBD is associated with low rate of recurrence – Am J GastroMasked bolus gluten challenge low in FODMAPs implicates nausea and vomiting as key shymptoms of exposure to celiac – AP&amp;TClinical and molecular features of post-colonoscopy colorectal cancers – CGHSimethicone use during gastrointestinal endoscopy: Position statement of the Gastroenterological Society of Australia – Journal of Gastro&amp;Hep Tweet

Show notes for Episodes 38 – January 2020 <ol><li><a href="http://giejournal.org/article/S0016-5107%2819%2932115-7/fulltext" rel="nofollow" target="_blank">ASGE review of adverse events in colonoscopy</a> – GIE </li><li><a href="https://www.nejm.org/doi/full/10.1056/NEJMoa1905380" rel="nofollow" target="_blank">Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia</a> – NEJM</li><li><a href="https://journals.lww.com/ajg/Fulltext/2019/12000/Relationship_Between_Recreational_Marijuana_Use.15.aspx" rel="nofollow" target="_blank">Relationship Between Recreational Marijuana  Use and Bowel Function in a Nationwide Cohort Study</a> – Am J gastro</li><li><a href="https://stm.sciencemag.org/content/12/524/eaax7533" rel="nofollow" target="_blank">Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and  screening for colorectal cancer</a> – Science TM</li><li><a href="https://www.ncbi.nlm.nih.gov/pubmed/31688023" rel="nofollow" target="_blank">Lactulose Breath Testing as a Predictor of  Response to Rifaximin in Patients With Irritable bowel  Syndrome With Diarrhea</a> – AmJ Gastro</li><li><a href="https://journals.lww.com/ajg/Fulltext/2019/10000/Postinfectious_Irritable_Bowel_Syndrome_After.16.aspx" rel="nofollow" target="_blank">Postinfectious IBS after Campylobacter infection</a> – Am J Gastro</li><li><a href="https://www.ncbi.nlm.nih.gov/pubmed/31470175" rel="nofollow" target="_blank">Oral Curcumin no more effective than placebo in preventing recurrence of Crohn’s disease after surgery in RTC</a> – CGH</li><li> <a href="https://journals.lww.com/ajg/Fulltext/2019/12000/Eradicating_H__pylori.1.aspx" rel="nofollow" target="_blank">Hpylori – when treat when not to treat</a> – Am J Gastro</li><li><a href="https://www.ncbi.nlm.nih.gov/pubmed/31714359" rel="nofollow" target="_blank">Long-Duration Oral Vancomycin to treat Cdiff in patients iwth IBD is associated with low rate of recurrence</a> – Am J Gastro</li><li><a href="https://onlinelibrary.wiley.com/doi/full/10.1111/apt.15551" rel="nofollow" target="_blank">Masked bolus gluten challenge low in FODMAPs implicates nausea and vomiting as key shymptoms of exposure to celiac</a> – AP&amp;T</li><li><a href="https://www.ncbi.nlm.nih.gov/pubmed/30930275" rel="nofollow" target="_blank">Clinical and molecular features of post-colonoscopy colorectal cancers</a> – CGH</li><li><a href="https://onlinelibrary.wiley.com/doi/full/10.1111/jgh.14757" rel="nofollow" target="_blank">Simethicone use during gastrointestinal endoscopy: Position statement of the Gastroenterological Society of Australia</a> – Journal of Gastro&amp;Hep</li></ol> <a href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fgipearls.com%2F2020%2F02%2F01%2Fgi-pearls-january-2020-episode-38-gastroenterology-literature-review%2F&amp;via=GI_Pearls" rel="nofollow" target="_blank">Tweet</a>

GI Pearls January 2020

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