Naveed Akbar's guest appearances

Naveed Akbar

Finding Genius Podcast

FutureTech Podcast

Terry Cralle

Kathryn Fantauzzi

Lawrence Bonassar

Kirsten Shockey

Richard Jacobs

Stephanie Schnorr

Jacob Koffler

Aric Prather

David Korsunsky

Michael Skinner

Jessica Pierce

Elisha Goldstein

Adam Brown

Indra Cidambi

Stacy Erickson

OwlTail

Dr. Akbar is interested in how our body’s over-response can cause protective inflammation in heart disease and strokes that does more harm in our metabolic systems. His extracellular vesicles research may hold the key to these signals. He describes:  Exactly how immunological responses to heart attacks cause inflammation that is ultimately harmful. Why atherosclerosis plaque buildup leads to an immune response that causes a cascade that leads to even more fat cell buildup. Why extracellular vesicles research into exact signals sent through the spleen may hold the key to adjusting these signals therapeutically.  Dr. Naveed Akbar focuses on extracellular vesicles research and metabolic disease. Atherosclerosis, a long-term condition that often leads to heart attacks and strokes through ruptures, exemplifies how our immune system and metabolic system have a helpful and harmful relationship. The connection between diabetics and worse manifestations of atherosclerosis holds an important clue to the signals that may be in play.  Atherosclerosis is a gradual condition that takes years to take hold and exists in a wide population. But what’s unclear is why diabetic patients have thicker and fattier plaques. Dr. Akbar believes this is because they have an immunological disease as well. This led to a stronger focus on immune system response to these conditions. Ultimately the various over-responses of the immune system increases the plaque layers and inflammation. Dr. Akbar discusses how his research attempts to engage or disengage these responses in appropriate ways. He especially is focused on extracellular vesicles research post metabolic disease. He’s found that immune cells travel to the heart and increase harmful inflammation. But by researching what signals cause this and how these signals can be manipulated, there’s hope for therapeutic responses. For more information, see his page on the Oxford University site: https://www.rdm.ox.ac.uk/people/naveed-akbar

Dr. Akbar is interested in how our body’s over-response can cause protective inflammation in heart disease and strokes that does more harm in our metabolic systems. His extracellular vesicles research may hold the key to these signals. He describes: <ul> <li>Exactly how immunological responses to heart attacks cause inflammation that is ultimately harmful.</li> <li>Why atherosclerosis plaque buildup leads to an immune response that causes a cascade that leads to even more fat cell buildup.</li> <li>Why extracellular vesicles research into exact signals sent through the spleen may hold the key to adjusting these signals therapeutically.</li> </ul> Dr. Naveed Akbar focuses on <a href="https://www.futuretechhealth.com/podcasts/future-clinical-applications-of-extracellular-vesicles-for-diagnosis-treatments-and-prognosis-dr-kenneth-witwer-associate-professor-of-molecular-and-comparative-pathobiology-and/" rel="noopener noreferrer nofollow" target="_blank">extracellular vesicles research</a> and metabolic disease. Atherosclerosis, a long-term condition that often leads to heart attacks and strokes through ruptures, exemplifies how our immune system and metabolic system have a helpful and harmful relationship. The connection between diabetics and worse manifestations of atherosclerosis holds an important clue to the signals that may be in play.  Atherosclerosis is a gradual condition that takes years to take hold and exists in a wide population. But what’s unclear is why diabetic patients have thicker and fattier plaques. Dr. Akbar believes this is because they have an immunological disease as well. This led to a stronger focus on immune system response to these conditions. Ultimately the various over-responses of the immune system increases the plaque layers and inflammation. Dr. Akbar discusses how his research attempts to engage or disengage these responses in appropriate ways. He especially is focused on extracellular vesicles research post metabolic disease. He’s found that immune cells travel to the heart and increase harmful inflammation. But by researching what signals cause this and how these signals can be manipulated, there’s hope for therapeutic responses. For more information, see his page on the Oxford University site: <a href="https://www.rdm.ox.ac.uk/people/naveed-akbar" rel="nofollow" target="_blank">https://www.rdm.ox.ac.uk/people/naveed-akbar</a>

Healing Signals and Immunological Response: Dr. Naveed Akbar Discusses the Complications of Inflammatory Results

While working at his post doc at Oxford University, Dr. Akbar focuses on the signals the immune system uses and resulting actions through extracellular vesicles research. He discusses:  How our body’s healing mechanisms post-heart attack can both benefit and undercut healthy arteries through immune-induced inflammation. The difference between a healthy blood vessel and atherosclerosis plaque build up and how the epithelial cell cascade that the body sends to heal the area ends up progressing the inflammatory condition. Why his research to turn on and off these inflammatory signals may aid in better healing from heart disease.  Dr. Naveed Akbar focuses on extracellular vesicles research and how the vesicles relate to metabolic disease. Atherosclerosis, which causes heart attacks and strokes, tends to be much thicker in a diabetic patient. He believes this junction of immunological and metabolic disease is an important crossroads.  He explains that while atherosclerosis builds up over decades due to many other lifestyle causes, we don't understand is why diabetic patients are more apt to get fattier plaques that are more aggressive and more prone to rupture, which ends in the heart attack and stroke events. Therefore, he has studied how immune systems responds to damage within the blood vessel and why immune cells accumulate within the wall of an artery to drive these attacks. They’ve discovered that as the monocytes try and engulf the fat in an artery, this action attracts more immune cells, causing more inflammation. Trying to understand what signals turn on and off the message to cause inflammation may lead to better healing. Finally, he describes a current project: extracellular vesicles research into what happens after a heart attack and splint placement. Immune cells go to the heart and create more inflammation, which is harmful—a healing that has a defective element. Understand what’s controlling their switch is important therapeutically. For more information, see his page on the Oxford University site: https://www.rdm.ox.ac.uk/people/naveed-akbar

While working at his post doc at Oxford University, Dr. Akbar focuses on the signals the immune system uses and resulting actions through <a href="https://www.futuretechpodcast.com/podcasts/exosomes-cancer-raghu-kalluri-md-phd-professor-and-chairman-department-of-cancer-biology-university-of-texas-md-anderson-cancer-center-seeking-to-understand-how-extracellula/" rel="noopener noreferrer nofollow" target="_blank">extracellular vesicles research</a>. He discusses: <ul> <li>How our body’s healing mechanisms post-heart attack can both benefit and undercut healthy arteries through immune-induced inflammation.</li> <li>The difference between a healthy blood vessel and atherosclerosis plaque build up and how the epithelial cell cascade that the body sends to heal the area ends up progressing the inflammatory condition.</li> <li>Why his research to turn on and off these inflammatory signals may aid in better healing from heart disease.</li> </ul> Dr. Naveed Akbar focuses on extracellular vesicles research and how the vesicles relate to metabolic disease. Atherosclerosis, which causes heart attacks and strokes, tends to be much thicker in a diabetic patient. He believes this junction of immunological and metabolic disease is an important crossroads.  He explains that while atherosclerosis builds up over decades due to many other lifestyle causes, we don't understand is why diabetic patients are more apt to get fattier plaques that are more aggressive and more prone to rupture, which ends in the heart attack and stroke events. Therefore, he has studied how immune systems responds to damage within the blood vessel and why immune cells accumulate within the wall of an artery to drive these attacks. They’ve discovered that as the monocytes try and engulf the fat in an artery, this action attracts more immune cells, causing more inflammation. Trying to understand what signals turn on and off the message to cause inflammation may lead to better healing. Finally, he describes a current project: extracellular vesicles research into what happens after a heart attack and splint placement. Immune cells go to the heart and create more inflammation, which is harmful—a healing that has a defective element. Understand what’s controlling their switch is important therapeutically. For more information, see his page on the Oxford University site: <a href="https://www.rdm.ox.ac.uk/people/naveed-akbar" rel="noopener noreferrer nofollow" target="_blank">https://www.rdm.ox.ac.uk/people/naveed-akbar</a>

Immunological Reactions and Heart Disease: Dr. Naveed Akbar Explains How our Body Hurts and Helps