Emma Rawlins's guest appearances

Emma Rawlins

The Stem Cell Podcast

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Guest:Dr. Emma Rawlins is a Senior Group Leader at the Gurdon Institute in the Department of Physiology, Development, and Neuroscience at the University of Cambridge. She talks about modeling fetal lung development using organoids, using single-cell RNA sequencing to create a human lung fetal atlas, and her advice to trainees to follow their hearts.Featured Products and Resources: Register for the ISSCR 2023 annual meeting Model the human respiratory system in vivo using PneumaCult™ The Stem Cell Science Round UpIn Vivo Reprogramming of Astrocytes into Neurons – Researchers refute that Ptbpt1 deletion induces astrocyte-to-neuron conversion.A Parkinson’s Drug for ALS  – Clinical trial results show that the Parkinson’s disease drug ropinirole delays ALS progression.Establishment of the Adult Blood System – Researchers identified miR-223 as a negative regulator of murine hemogenic endothelial cell specification and myelopoiesis.Modeling Preneoplasia in Gastric Organoids – Gastric organoids with inactivated TP53, a common early event in gastric cancer, were created to model the earliest events in human tumor initiation.Photo Reference: Courtesy of Emma Rawlins.	#footable_5807  {    font-family: inherit; 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<h3>Guest:</h3>Dr. Emma Rawlins is a Senior Group Leader at the Gurdon Institute in the Department of Physiology, Development, and Neuroscience at the University of Cambridge. She talks about <a href="https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(22)00460-X" rel="nofollow" target="_blank">modeling fetal lung development using organoids</a>, using single-cell RNA sequencing to create a <a href="https://www.cell.com/cell/fulltext/S0092-8674(22)01415-5" rel="nofollow" target="_blank">human lung fetal atlas</a>, and her advice to trainees to follow their hearts.<h3>Featured Products and Resources:</h3><ul> <li><a href="https://www.isscr2023.org/?utm_source=scpodcast&amp;utm_medium=banner" rel="nofollow" target="_blank">Register for the ISSCR 2023 annual meeting</a></li> <li><a href="https://www.stemcell.com/products/brands/pneumacult.html?utm_source=scpodcast&amp;utm_medium=banner" rel="nofollow" target="_blank">Model the human respiratory system in vivo using PneumaCult™</a></li> </ul><h3>The Stem Cell Science Round Up</h3><a href="https://www.nature.com/articles/s41586-023-06066-9" rel="nofollow" target="_blank">In Vivo Reprogramming of Astrocytes into Neurons</a> – Researchers refute that Ptbpt1 deletion induces astrocyte-to-neuron conversion.<a href="https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(23)00135-2" rel="nofollow" target="_blank">A Parkinson’s Drug for ALS</a>  – Clinical trial results show that the Parkinson’s disease drug ropinirole delays ALS progression.<a href="https://www.cell.com/developmental-cell/fulltext/S1534-5807(23)00240-X" rel="nofollow" target="_blank">Establishment of the Adult Blood System</a> – Researchers identified miR-223 as a negative regulator of murine hemogenic endothelial cell specification and myelopoiesis.<a href="https://www.nature.com/articles/s41586-023-06102-8" rel="nofollow" target="_blank">Modeling Preneoplasia in Gastric Organoids</a> – Gastric organoids with inactivated TP53, a common early event in gastric cancer, were created to model the earliest events in human tumor initiation.Photo Reference: Courtesy of Emma Rawlins.	 #footable_5807 { font-family: inherit; 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} .semantic_ui .ui.table td { padding: 0em; } #footable_5808 { font-family: inherit; font-size: 14px; } thead { display: none; } #footable_parent_5808 a.nt_edit_link { display: none; } #footable_parent_5808 td { border-color: #fff; } #footable_parent_5808 img { margin-top: 0px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } <h3>Subscribe to our newsletter!</h3> Never miss updates about new episodes. <a href="/newsletter" rel="nofollow" target="_blank">Subscribe</a>

Ep. 244: “The Mammalian Lung” Featuring Dr. Emma Rawlins

In today’s episode, Dr Emma Rawlins, a senior group leader at the Gurdon Institute in University of Cambridge. She is interviewed by PhD student Elena Drudi. Emma talks about her research on stem cells in mammalian lungs using both mouse and human organoid models. She discusses the pros and cons of the two models. She describes her research interest in understanding normal embryonic lung development, with the aim to further repurpose these cues for lung repair/regeneration in adults. She emphasises how functional human genetics on a population level, in combination with human organoids models, can further help dissecting diseases susceptibility and regeneration. She also shares her journey from studying drosophila to human lung biology, and how going aboard no longer seems to be a necessity to continue one's career. To learn more about Emma’s recent postdoc work, check out the following links: https://www.gurdon.cam.ac.uk/research/rawlins

In today’s episode, Dr Emma Rawlins, a senior group leader at the Gurdon Institute in University of Cambridge. She is interviewed by PhD student Elena Drudi. Emma talks about her research on stem cells in mammalian lungs using both mouse and human organoid models. She discusses the pros and cons of the two models. She describes her research interest in understanding normal embryonic lung development, with the aim to further repurpose these cues for lung repair/regeneration in adults. She emphasises how functional human genetics on a population level, in combination with human organoids models, can further help dissecting diseases susceptibility and regeneration. She also shares her journey from studying drosophila to human lung biology, and how going aboard no longer seems to be a necessity to continue one's career. To learn more about Emma’s recent postdoc work, check out the following links: <a href="https://www.gurdon.cam.ac.uk/research/rawlins" rel="nofollow" target="_blank">https://www.gurdon.cam.ac.uk/research/rawlins</a>

Episode 140- Dr Emma Rawlins "I'll look at stem cell in any systems"

In this episode, Dr Emma Rawlins joins us to discuss how our understanding of lung development has changed, and how this might allow us to regenerate lung damage therapeutically.How do our lungs develop from progenitor cells? How can stem cell populations respond to damage and disease in adults? How can these insights be leveraged to regenerate the lung following damage or disease?Some of the topics we cover include:Rare lung cell types important in regenerationHuman lung organoids and modeling SARS-CoV-2 infection The strengths and limitations of single-cell RNA sequencing in the fieldCell therapies and endogenous strategies for repairing the lungEmma is a Senior Group Leader at Cambridge University's Gurdon Institute. Her lab investigates stem and progenitor cells in the lung. 

In this episode, Dr Emma Rawlins joins us to discuss how our understanding of lung development has changed, and how this might allow us to regenerate lung damage therapeutically. How do our lungs develop from progenitor cells? How can stem cell populations respond to damage and disease in adults? How can these insights be leveraged to regenerate the lung following damage or disease? Some of the topics we cover include: Rare lung cell types important in regeneration Human lung organoids and modeling SARS-CoV-2 infection  The strengths and limitations of single-cell RNA sequencing in the field Cell therapies and endogenous strategies for repairing the lung Emma is a Senior Group Leader at Cambridge University's Gurdon Institute. Her lab investigates stem and progenitor cells in the lung.

Development and Regeneration of the Lung with Emma Rawlins