Dmitry Ter-Ovanesyan's guest appearances

Dmitry Ter-Ovanesyan

Finding Genius Podcast

FutureTech Podcast

Laura Potterat

Marc Guell

Paul Turner

Jan Vijg

Eleftherios Mylonakis

Cory Kidd

Charles C.J

Helius Medical Technologies

Patrick McKeown

Michael G. Surette

Katelyn Parsons

John Tucker

Jake Kushner

Erik Gunther

Kim Kush

OwlTail

In 2007, two papers announced exciting news: extracellular vesicles (EVs) hold RNA and not just garbage from the cell as had been thought. In this podcast, Dr. Ter-Ovanesyan talks about:  The importance of locating RNA outside of cellular borders. The interesting challenges EVs present to synthetic biology research and extracellular vesicles research such as disagreements over isolating procedures. The substantial solutions for illnesses Dr. Ter-Ovanesyan believes exosomes (another term for EVs) could offer, such as understanding and preventing dementia.  Dr. Dmitry Ter-Ovanesyan is a post-doc at Harvard with the Wyss Institute in extracellular vesicles research. As an undergraduate student, he was captivated when the RNA discovery was published by what he thought these exosomes might mean and what they might be capable of in the medical world.  EVs have been known to exist for 40 years, but these 2007 studies revealed that they contain RNA through electron microscopy. A significant finding due to extracellular RNA existence, the scientific community paid attention. Dr. Ter-Ovanesyan discusses why RNA traveling between cells is so important. He also explains the various roadblocks researchers face in using these exosomes: it is very difficult to both effectively isolate and distinguish them because unlike a virus, there's no distinguishing protein they present. However, they hold tremendous promise for the medical field, such as possibly supplying RNA-level clues about the heart or brain without invasive procedures. They also might offer RNA drug potential through synthetic biology research.  For more information, see his contact information on the Wyss Institute page (https://wyss.harvard.edu/team/research-scientists-engineers/dima-ter-ovanesyan/_ and Harvard's Church Lab page (https://genetics.med.harvard.edu/lab/church/dter-ovanesyan). His publications are listed on PubMed as well.

In 2007, two papers announced exciting news: extracellular vesicles (EVs) hold RNA and not just garbage from the cell as had been thought. In this podcast, Dr. Ter-Ovanesyan talks about: <ul> <li>The importance of locating RNA outside of cellular borders.</li> <li>The interesting challenges EVs present to synthetic biology research and extracellular vesicles research such as disagreements over isolating procedures.</li> <li>The substantial solutions for illnesses Dr. Ter-Ovanesyan believes exosomes (another term for EVs) could offer, such as understanding and preventing dementia.</li> </ul> Dr. Dmitry Ter-Ovanesyan is a post-doc at Harvard with the <a href="https://wyss.harvard.edu/" rel="nofollow" target="_blank">Wyss Institute</a> in extracellular vesicles research. As an undergraduate student, he was captivated when the RNA discovery was published by what he thought these exosomes might mean and what they might be capable of in the medical world.  EVs have been known to exist for 40 years, but these 2007 studies revealed that they contain RNA through electron microscopy. A significant finding due to extracellular RNA existence, the scientific community paid attention. Dr. Ter-Ovanesyan discusses why RNA traveling between cells is so important. He also explains the various roadblocks researchers face in using these exosomes: it is very difficult to both effectively isolate and distinguish them because unlike a virus, there's no distinguishing protein they present. However, they hold tremendous promise for the medical field, such as possibly supplying RNA-level clues about the heart or brain without invasive procedures. They also might offer RNA drug potential through synthetic biology research.  For more information, see his contact information on the <a href="https://wyss.harvard.edu/" rel="nofollow" target="_blank">Wyss Institute</a> page (<a href="https://wyss.harvard.edu/team/research-scientists-engineers/dima-ter-ovanesyan/" rel="nofollow" target="_blank">https://wyss.harvard.edu/team/research-scientists-engineers/dima-ter-ovanesyan/</a>_ and Harvard's Church Lab page (<a href="https://genetics.med.harvard.edu/lab/church/dter-ovanesyan" rel="nofollow" target="_blank">https://genetics.med.harvard.edu/lab/church/dter-ovanesyan</a>). His publications are listed on <a href="https://pubmed.ncbi.nlm.nih.gov/" rel="nofollow" target="_blank">PubMed</a> as well.

RNA-Carrying Extracellular Vesicles: Dr. Dmitry Ter-Ovanesyan

After a discovery ten years ago showed that extracellular vesicles (EVs) contain RNA rather than just cell waste, Dr. Ter-Ovanesyan has studied these cellular products. This discussion explores:   Why it's significant that RNA is shown to exist outside of cellular boundaries. What puzzles scientists need to solve to use EVs for new solutions in synthetic biology research. The significant advances in health that EVs, also called exosomes, may offer, such as ways to address dementia, and already-developed technology such as detecting prostate cancer through finding EVs in the urine.   Dr. Dmitry Ter-Ovanesyan is working as a post-doc at Harvard with the Wyss Institute in extracellular vesicle research. He's drawn to the great potential and challenges these exosomes offer scientists in solving multiple health issues. While EVs were discovered about 40 years ago, it wasn't until two studies published in 2007 announced that they contained RNA that the scientific community focused more energy their way. Dr. Ter-Ovanesyan was a student at the time and was immediately drawn to these RNA-carrying vesicles. He explains why RNA is so significant in the complexity of messages it might carry from one cell to another. He also describes the multiple challenges these exosomes present because of their heterogeneous nature and difficulties in isolating them. But he recounts the great potential they may offer, from offering doctors information about the brain or heart by supplying RNA information to RNA drug possibilities through synthetic biology research. For more information, see his contact information on the Wyss Institute page (https://wyss.harvard.edu/team/research-scientists-engineers/dima-ter-ovanesyan/_ and Harvard's Church Lab page (https://genetics.med.harvard.edu/lab/church/dter-ovanesyan). His publications are listed on PubMed as well.

After a discovery ten years ago showed that extracellular vesicles (EVs) contain RNA rather than just cell waste, Dr. Ter-Ovanesyan has studied these cellular products. This discussion explores: <ul> <li>Why it's significant that RNA is shown to exist outside of cellular boundaries.</li> <li>What puzzles scientists need to solve to use EVs for new solutions in synthetic biology research.</li> <li>The significant advances in health that EVs, also called exosomes, may offer, such as ways to address dementia, and already-developed technology such as detecting prostate cancer through finding EVs in the urine.</li> </ul> Dr. Dmitry Ter-Ovanesyan is working as a post-doc at Harvard with the <a href="https://wyss.harvard.edu/" rel="nofollow" target="_blank">Wyss Institute</a> in extracellular vesicle research. He's drawn to the great potential and challenges these exosomes offer scientists in solving multiple health issues. While EVs were discovered about 40 years ago, it wasn't until two studies published in 2007 announced that they contained RNA that the scientific community focused more energy their way. Dr. Ter-Ovanesyan was a student at the time and was immediately drawn to these RNA-carrying vesicles. He explains why RNA is so significant in the complexity of messages it might carry from one cell to another. He also describes the multiple challenges these exosomes present because of their heterogeneous nature and difficulties in isolating them. But he recounts the great potential they may offer, from offering doctors information about the brain or heart by supplying RNA information to RNA drug possibilities through synthetic biology research. For more information, see his contact information on the <a href="https://wyss.harvard.edu/" rel="nofollow" target="_blank">Wyss Institute</a> page (<a href="https://wyss.harvard.edu/team/research-scientists-engineers/dima-ter-ovanesyan/" rel="nofollow" target="_blank">https://wyss.harvard.edu/team/research-scientists-engineers/dima-ter-ovanesyan/</a>_ and Harvard's Church Lab page (<a href="https://genetics.med.harvard.edu/lab/church/dter-ovanesyan" rel="nofollow" target="_blank">https://genetics.med.harvard.edu/lab/church/dter-ovanesyan</a>). His publications are listed on <a href="https://pubmed.ncbi.nlm.nih.gov/" rel="nofollow" target="_blank">PubMed</a> as well.

Extracellular Vesicles Research: Dr. Dmitry Ter-Ovanesyan Explains the Exciting Potential and Challenges Ahead