Jacob Koffler's guest appearances

Jacob Koffler

Finding Genius Podcast

FutureTech Podcast

Naveed Akbar

Marc Guell

Laura Potterat

Jan Vijg

Paul Turner

Eleftherios Mylonakis

Cory Kidd

Charles C.J

Helius Medical Technologies

Patrick McKeown

Michael G. Surette

Katelyn Parsons

John Tucker

Jake Kushner

Erik Gunther

OwlTail

When a patient presents to the ER with a heart problem, most doctors will know what tests to run, what drugs to prescribe, and what treatment will be best for recuperating that patient and allowing them to go home and resume their normal lives. The same cannot be said for those who present to the ER with a spinal cord injury. In fact, there is no proper treatment for spinal cord injuries, and therefore a big need for new research and development in this field. When Jacob Koffler finished his PhD in biomedical engineering in 2010, this is exactly what he was looking for: a field where there was a big need for new ideas and techniques in the development of a successful treatment. He brings a tremendous amount of information to the conversation today, discussing his efforts at UC San Diego toward developing a treatment for spinal cord injuries. The technique he’s helping develop involves stem cells, 3D printing of tissue scaffolds, and gene expression studies of nerve regeneration.  Tune in for all the details.  

<p>When a patient presents to the ER with a heart problem, most doctors will know what tests to run, what drugs to prescribe, and what treatment will be best for recuperating that patient and allowing them to go home and resume their normal lives. The same cannot be said for those who present to the ER with a spinal cord injury. In fact, there is no proper treatment for spinal cord injuries, and therefore a big need for new research and development in this field. When Jacob Koffler finished his PhD in biomedical engineering in 2010, this is exactly what he was looking for: a field where there was a big need for new ideas and techniques in the development of a successful treatment. He brings a tremendous amount of information to the conversation today, discussing his efforts at UC San Diego toward developing a treatment for spinal cord injuries. The technique he’s helping develop involves stem cells, 3D printing of tissue scaffolds, and gene expression studies of nerve regeneration. </p> <p>Tune in for all the details.  </p>

Gene Expression Studies and Spinal Cord Injury Repair—Jacob Koffler—UC San Diego Neural Engineering Lab

After receiving a PhD in biomedical engineering, Jacob Koffler wanted to take what he’d learned into a new field where there was a big need for biomedical solutions and research. This desire led him into the field of spinal cord injury repair in 2010, when there wasn’t much being done to advance treatments using the interdisciplinary approach of biomedical engineering. With a strong belief that tissue engineering could contribute to the development of a successful treatment for spinal cord injuries, Dr. Koffler has been working at UC San Diego with this goal in mind. On today’s episode, he discusses the unique technique they’re using to tackle this problem, which involves 3D printing, tissue engineering of scaffolds and longitudinal linear channels, implementation of stem cells to elicit nerve regeneration, and perhaps most importantly, a study of gene expression after regeneration has been elicited, in order to better understand it and promote additional regeneration. He describes the ins and out of the science behind this approach, and also touches on the difference between the peripheral and central nervous system when it comes to nerve regeneration, nerve growth and development in juveniles, the role of stem cells in spinal cord repair, the nature of ongoing studies in the field, and so much more.

Nerve Regeneration, Working Toward a Treatment for Spinal Cord Injury, Jacob Koffler- UC San Diego Neural Engineering Lab