Beatrix Suess's guest appearances

Beatrix Suess

iBiology: Subtitled versions

iBiology Techniques

Jens Nielsen

Janet Iwasa

Timothy Lu

Steve Busby

Jay Keasling

Steffen Schmitt

Malte Paulsen

Tobias Erb

David Bikard

Victor de Lorenzo

Wendell Lim

Eriko Takano

Emma Frow

Susanne Heck

Vivek Mutalik

OwlTail

Riboswitches are highly structured RNA elements that are located in the 5’ UTR of many bacterial mRNAs.  Riboswitches bind ligands with high specificity. This causes a termination of transcription or the inhibition of translation initiation. Dr. Suess explains that it is possible to select for RNA aptamers that bind a specific ligand, such as tetracyline or neomycin, and engineer these into the 5’ region of a yeast mRNA allowing gene expression to be regulated by adding ligand. Suess discusses what makes an aptamer into a riboswitch. http://www.ibiology.org/ibioeducation/mechanistic-insights-engineered-riboswitches.htmlSpeaker Biography:Beatrix Suess is a Professor at the Technical University, Darmstadt.  She received her PhD from the University of Erlangen, Germany where she was also a post-doctoral fellow. Suess was also a research fellow at the University of Vienna, Austria and at Yale University, USA.  Dr. Suess’s research focuses on the ability of RNA to operate as a regulator of activities within the cell. In particular, her work focuses on the use of riboswitches as regulatory devices in synthetic biology applications.

Riboswitches are highly structured RNA elements that are located in the 5’ UTR of many bacterial mRNAs. Riboswitches bind ligands with high specificity. This causes a termination of transcription or the inhibition of translation initiation. Dr. Suess explains that it is possible to select for RNA aptamers that bind a specific ligand, such as tetracyline or neomycin, and engineer these into the 5’ region of a yeast mRNA allowing gene expression to be regulated by adding ligand. Suess discusses what makes an aptamer into a riboswitch. <a href="http://www.ibiology.org/ibioeducation/mechanistic-insights-engineered-riboswitches.html" rel="nofollow" target="_blank">http://www.ibiology.org/ibioeducation/mechanistic-insights-engineered-riboswitches.html</a> Speaker Biography: Beatrix Suess is a Professor at the Technical University, Darmstadt. She received her PhD from the University of Erlangen, Germany where she was also a post-doctoral fellow. Suess was also a research fellow at the University of Vienna, Austria and at Yale University, USA. Dr. Suess’s research focuses on the ability of RNA to operate as a regulator of activities within the cell. In particular, her work focuses on the use of riboswitches as regulatory devices in synthetic biology applications.

Synthetic Biology: Mechanistic Insights into Engineered Riboswitches - Beatrix Suess