Sage Bionetworks's guest appearances

Sage Bionetworks

Against The Grain - The Podcast

AWS re:Invent 2017

re:Invent re:Dux

The EPAM Continuum Podcast Network

The ORION Open Science Podcast

Eric Topol

Eli Lilly

Elisabeth Rosenthal

Maurício Manhães

Mike Gorman

Aubrey de Grey

Alan Rusbridger

Megan Burns

John Ioannidis

David Stewart

Amazon Athena

Steven Novella

Jessica Helfand

Amy Virshup

Noreena Hertz

OwlTail

Episode Summary:  This week we talk to Lara Mangravite, President of Sage Bionetworks 'a nonprofit biomedical research and technology development organization' that facilitates research data sharing in biomedicine, as well as promoting community research and citizen science projects. We discussed the advantages and challenges of dating sharing and what tools Sage BioNetworks are offering*.  Episode Links (provided by Sage Bionetworks):  Synapse is a set of web services and tools created by Sage Bionetworks that make it easier for researchers to aggregate, organize, analyze, and share scientific data, code, and insights. mPower is a free, 2 year digital health research study developed with the goal of understanding the progression of Parkinson’s Disease at the level of the individual. Elements of Informed Consent is a free, downloadable toolkit for researchers that includes basic information and best practices for developing an effective informed consent process. The Open Drug Discovery Center for AD (Open AD) was established to develop and openly distribute experimental tools for use in the evaluation of a diverse set of novel AD targets.  Other Links: Center for Open Science , NIH All of Us Research Program, Structural Genomics Consortium   *"The thoughts and views expressed in this interview are Lara Mangravite's and not those of Sage Bionetworks or any affiliated organizations."

Episode Summary:  This week we talk to Lara Mangravite, President of Sage Bionetworks 'a nonprofit biomedical research and technology development organization' that facilitates research data sharing in biomedicine, as well as promoting community research and citizen science projects. We discussed the advantages and challenges of dating sharing and what tools Sage BioNetworks are offering*.  Episode Links (provided by Sage Bionetworks):  <a href="http://synapse.org/" rel="nofollow" target="_blank">Synapse</a> is a set of web services and tools created by <a href="https://sagebionetworks.org/" rel="nofollow" target="_blank">Sage Bionetworks</a> that make it easier for researchers to aggregate, organize, analyze, and share scientific data, code, and insights. <a href="https://parkinsonmpower.org/your-story" rel="nofollow" target="_blank">mPower</a> is a free, 2 year digital health research study developed with the goal of understanding the progression of Parkinson’s Disease at the level of the individual. <a href="https://sagebionetworks.org/tools_resources/elements-of-informed-consent/" rel="nofollow" target="_blank">Elements of Informed Consent</a> is a free, downloadable toolkit for researchers that includes basic information and best practices for developing an effective informed consent process. The <a href="https://www.nia.nih.gov/news/nih-funded-translational-research-centers-speed-diversify-alzheimers-drug-discovery" rel="nofollow" target="_blank">Open Drug Discovery Center for AD (Open AD)</a> was established to develop and openly distribute experimental tools for use in the evaluation of a diverse set of novel AD targets.  Other Links: <a href="https://cos.io/" rel="nofollow" target="_blank">Center for Open Science</a> , <a href="https://allofus.nih.gov/" rel="nofollow" target="_blank">NIH All of Us Research Program</a>, <a href="https://www.thesgc.org/" rel="nofollow" target="_blank">Structural Genomics Consortium</a> *"The thoughts and views expressed in this interview are Lara Mangravite's and not those of Sage Bionetworks or any affiliated organizations."

Together Works Better: How Sage Bionetworks Use A Collective Approach To Data

DREAM Challenges pose fundamental questions about systems biology and translational medicine. Designed and run by a community of researchers from a variety of organizations, the challenges invite participants to propose solutions, fostering collaboration and building communities in the process. The Sage Bionetworks Synapse platform, which powers many research consortiums including the DREAM Challenges, are starting to put into practice model cloud-initiatives that not only provide impactful discoveries in the areas of neuroscience, infectious disease, and cancer, but are also revolutionizing scientific research by enabling an interactive consortium science platform. In this session, you learn how to build a "consortium model" of research in order to connect research organizations with non-profit organizations, technology companies, biotechnology, and pharmaceutical companies. You can also learn about how to leverage machine learning, Amazon ECS, and R for consortium-based science initiatives.

LFS301: SAGE Bionetworks, the Digital Mammography DREAM Challenge and How AWS Enables Consortium Science to Accelerate Discovery

John Wilbanks

John Wilbanks, Chief Commons Officer of Sage Bionetworks, says “the very containers” that we used to put data in, “that kept it human-scale,” have been “blown to bits.” The question is: How do we pick up the pieces and reassemble them in the aftermath? In this "Resonance Test" podcast, Wilbanks and Continuum SVP Mike Dunkley dive down into the many issues surrounding healthcare data. “We basically throw darts at the dartboard with a blindfold on right now," says Wilbanks. “Using data, statistical modeling, and machine learning *has* to be better than that.” Together, Wilbanks and Dunkley talk about smartphones and increasing sample size in health research, the idea of a “credit union” for data, and the challenge of measuring the success of precision medicine. The work is, for the passionate Wilbanks, a very human-centric activity. “Health is personal," he says. "Experience of disease is personal. Lived experience is personal, and you can start to capture these lived experiences and aggregate them in ways that tell us a lot about disease that we didn’t used to know.”

The Resonance Test 3: John Wilbanks of Sage Bionetworks