Gary Karpen's guest appearances

Gary Karpen

Epigenetics Podcast

Joe Fernandez

David Jones

Monica Dus

Karmella Haynes

Erez Lieberman Aiden

Noe Gonzalez

Shelley Berger

Emily Bernstein

Wendy Bickmore

Susan Gasser

Henk Stunnenberg

Peter Tessarz

Adam Blattler

Don Olins

Markus Buschbeck

OwlTail

Heterochromatin plays a pivotal role in organizing our genome in the nucleus and separating active from inactive genomic regions. In this Podcast Episode our Guest Gary Karpen from UC Berkeley sits down with our Host Stefan Dillinger to talk about the regulation of this chromatin structure and how DNA repair mechanisms function in this densely packed nuclear compartment. Furthermore, they also discuss how phase separation might be an important part in how heterochromatin domains are formed. References  Jamy C. Peng, Gary H. Karpen (2009) Heterochromatic Genome Stability Requires Regulators of Histone H3 K9 Methylation (PLoS Genetics) DOI: 10.1371/journal.pgen.1000435 Peter V. Kharchenko, Artyom A. Alekseyenko, … Peter J. Park (2011) Comprehensive analysis of the chromatin landscape in Drosophila melanogaster (Nature) DOI: 10.1038/nature09725 Aniek Janssen, Serafin U. Colmenares, … Gary H. Karpen (2019) Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A (Genes &amp; Development) DOI: 10.1101/gad.317537.118  Amy R. Strom, Alexander V. Emelyanov, … Gary H. Karpen (2017) Phase separation drives heterochromatin domain formation (Nature) DOI: 10.1038/nature22989  Contact https://twitter.com/activemotif  https://twitter.com/epigenetics_pod  https://www.linkedin.com/company-beta/35651/  https://www.facebook.com/ActiveMotifInc/  https://activemotif.com/blog  podcast@activemotif.com

Heterochromatin plays a pivotal role in organizing our genome in the nucleus and separating active from inactive genomic regions. In this Podcast Episode our Guest Gary Karpen from UC Berkeley sits down with our Host Stefan Dillinger to talk about the regulation of this chromatin structure and how DNA repair mechanisms function in this densely packed nuclear compartment. Furthermore, they also discuss how phase separation might be an important part in how heterochromatin domains are formed. References <ul><li>Jamy C. Peng, Gary H. Karpen (2009) <a href="https://dx.plos.org/10.1371/journal.pgen.1000435" rel="nofollow" target="_blank">Heterochromatic Genome Stability Requires Regulators of Histone H3 K9 Methylation</a> (PLoS Genetics) DOI: <a href="http://dx.doi.org/10.1371/journal.pgen.1000435" rel="nofollow" target="_blank">10.1371/journal.pgen.1000435</a></li> <li>Peter V. Kharchenko, Artyom A. Alekseyenko, … Peter J. Park (2011) <a href="http://www.nature.com/articles/nature09725" rel="nofollow" target="_blank">Comprehensive analysis of the chromatin landscape in Drosophila melanogaster</a> (Nature) DOI: <a href="http://dx.doi.org/10.1038/nature09725" rel="nofollow" target="_blank">10.1038/nature09725</a></li> <li>Aniek Janssen, Serafin U. Colmenares, … Gary H. Karpen (2019) <a href="http://genesdev.cshlp.org/lookup/doi/10.1101/gad.317537.118" rel="nofollow" target="_blank">Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A</a> (Genes &amp; Development) DOI: <a href="http://dx.doi.org/10.1101/gad.317537.118" rel="nofollow" target="_blank">10.1101/gad.317537.118</a> </li> <li>Amy R. Strom, Alexander V. Emelyanov, … Gary H. Karpen (2017) <a href="http://www.nature.com/articles/nature22989" rel="nofollow" target="_blank">Phase separation drives heterochromatin domain formation</a> (Nature) DOI: <a href="http://dx.doi.org/10.1038/nature22989" rel="nofollow" target="_blank">10.1038/nature22989</a></li> </ul> Contact <ul><li><a href="https://twitter.com/activemotif" rel="nofollow" target="_blank">https://twitter.com/activemotif </a></li> <li><a href="https://twitter.com/epigenetics_pod" rel="nofollow" target="_blank">https://twitter.com/epigenetics_pod </a></li> <li><a href="https://www.linkedin.com/company-beta/35651/" rel="nofollow" target="_blank">https://www.linkedin.com/company-beta/35651/ </a></li> <li><a href="https://www.facebook.com/ActiveMotifInc/" rel="nofollow" target="_blank">https://www.facebook.com/ActiveMotifInc/ </a></li> <li><a href="https://activemotif.com/blog" rel="nofollow" target="_blank">https://activemotif.com/blog </a></li> <li>podcast@activemotif.com</li></ul>

Heterochromatin and Phase Separation (Gary Karpen)