Volker Straub's guest appearances

Volker Straub

This Month in Muscular Dystrophy

Decoding Duchenne

Scott Harper

Paul Martin

Hugh Allen

Alex Johnson

Andy Farrell

Collagen VI

Jeff Chamberlain

Kate Bushby

Jerry Mendell

Louis Chicoine

James Ervasti

Francesco Muntoni

Louise Rodino-Klapac

Denis Guttridge

Jill Rafael-Fortney

OwlTail

Emily Crossley

Emma Helsop

Our host Clare Runacres speaks about the DMD Hub with Prof Volker Straub - Professor of Medicine and Professor of Neuromuscular Genetics at Newcastle University, Emma Heslop - DMD Hub manager and Duchenne UK's co-founders Alex Johnson and Emily Crossley.Visit dmdhug.org                If you have any questions please email support@duchenneuk.org

Our host Clare Runacres speaks about the DMD Hub with Prof Volker Straub - Professor of Medicine and Professor of Neuromuscular Genetics at Newcastle University, Emma Heslop - DMD Hub manager and Duchenne UK's co-founders Alex Johnson and Emily Crossley. Visit <a href="http://dmdhug.org" rel="nofollow" target="_blank">dmdhug.org</a> If you have any questions please email support@duchenneuk.org

8. The DMD Hub - Alex Johnson, Emily Crossley, Prof Volker Straub and Emma Helsop

In this podcast we speak with  Prof Volker Straub about Testosterone, which is sometimes given to patients with Duchenne Muscular Dystrophy (DMD) who take steroids.Steroids are part of the recognised standard of care in treating Duchenne Muscular Dystrophy (DMD). But long-term use of steroids causes a number of side effects including delayed puberty. Testosterone is sometimes given to make boys begin going through puberty. There is a clinical trial running at the John Walton Muscular Dystrophy Research Centre (JWMDRC), led by Prof Volker Straub and Dr Claire Wood, treating 15 adolescents with DMD with testosterone to induce puberty. As well as looking at the effect of testosterone on pubertal development, growth, muscle strength and function, bone mineral density and body composition, the trial is looking at the mood, quality of life and well-being of patients to assess their satisfaction with the benefits of the treatment compared to the side effects.Duchenne UK has granted £228,562.51 to pay for the extension study of this trial to look at the longer term effects of testosterone treatment following earlier treatment to induce puberty. The extension study will investigate whether testosterone treatment to induce puberty will be enough to support long term testosterone production, or whether further treatment with testosterone is needed for patients on long-term steroids to keep producing testosterone, even if puberty was successfully induced.

In this podcast we speak with Prof Volker Straub about Testosterone, which is sometimes given to patients with Duchenne Muscular Dystrophy (DMD) who take steroids. Steroids are part of the recognised standard of care in treating Duchenne Muscular Dystrophy (DMD). But long-term use of steroids causes a number of side effects including delayed puberty. Testosterone is sometimes given to make boys begin going through puberty. There is a clinical trial running at the John Walton Muscular Dystrophy Research Centre (JWMDRC), led by Prof Volker Straub and Dr Claire Wood, treating 15 adolescents with DMD with testosterone to induce puberty. As well as looking at the effect of testosterone on pubertal development, growth, muscle strength and function, bone mineral density and body composition, the trial is looking at the mood, quality of life and well-being of patients to assess their satisfaction with the benefits of the treatment compared to the side effects. Duchenne UK has granted £228,562.51 to pay for the extension study of this trial to look at the longer term effects of testosterone treatment following earlier treatment to induce puberty. The extension study will investigate whether testosterone treatment to induce puberty will be enough to support long term testosterone production, or whether further treatment with testosterone is needed for patients on long-term steroids to keep producing testosterone, even if puberty was successfully induced.

6. SPECIAL EPISODE - Testosterone as a treatment for DMD with Prof Volker Straub

Dr. Volker Straub Discusses the Use of Muscle MRI in Muscular DystrophyGuest: Volker Straub, MD, PhD, Harold Macmillan Professor of Medicine and Professor of neuromuscular genetics at the University of Newcastle upon Tyne in the United Kingdom.Access an abstract of this month’s featured research articles: - Quantitative Muscle MRI as an Assessment Tool for Monitoring Disease Progression in LGMD2I: A Multicentre Longitudinal Study. PLoS One. 2013 Aug 14, 8(8):e70993.- MR imaging in Duchenne muscular dystrophy: Longitudinal assessment of natural history over 18 months. Muscle Nerve. 2013 Apr 26.

Dr. Volker Straub Discusses the Use of Muscle MRI in Muscular Dystrophy Guest: Volker Straub, MD, PhD, Harold Macmillan Professor of Medicine and Professor of neuromuscular genetics at the University of Newcastle upon Tyne in the United Kingdom. Access an abstract of this month’s featured research articles: - Quantitative Muscle MRI as an Assessment Tool for Monitoring Disease Progression in LGMD2I: A Multicentre Longitudinal Study. PLoS One. 2013 Aug 14, 8(8):e70993. - MR imaging in Duchenne muscular dystrophy: Longitudinal assessment of natural history over 18 months. Muscle Nerve. 2013 Apr 26.

Dr. Volker Straub Discusses the Use of Muscle MRI in Muscular Dystrophy